In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair.
- AnnotationStudy presents the high-resolution crystal structure of the Arch domain of XPD with its interaction partner MAT1 a central component of the CDK activating kinase complex. The analysis of the interface led to the identification of amino acid residues that are crucial for the MAT1-XPD interaction.
- CategoryInteraction
- SourceGeneRif: 4331