Study presents the high-resolution crystal structure of the Arch domain of XPD with its interaction partner MAT1 a central component of the CDK activating kinase complex. The analysis of the interface led to the identification of amino acid residues that are crucial for the MAT1-XPD interaction.
Observational study of gene-disease association gene-gene interaction and gene-environment interaction. (HuGE Navigator); These results suggested that genetic variants in CAK genes Cdk7 cyclin H MAT1 might modulate the risk of lung cancer in a gene-gene interaction mode which consist to the biochemical interaction of corresponding proteins.
Retinoic-acid-induced RAR-CAK signaling events appear to proceed intrinsically during granulocytic development of normal primitive hematopoietic cells. ALDH-governed RA availability may mediate this process by initiating RAR-CAK signaling.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.