A0A024KZ56 · A0A024KZ56_ECOLX

  • Protein
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • Gene
    bioH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

Pathway

Cofactor biosynthesis; biotin biosynthesis.

Features

Showing features for binding site, active site.

125620406080100120140160180200220240
TypeIDPosition(s)Description
Binding site22substrate
Active site82Nucleophile
Binding site82-83substrate
Binding site143-147substrate
Active site207
Active site235
Binding site235substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpimelyl-[acyl-carrier protein] methyl ester esterase activity
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • EC number
  • Alternative names
    • Biotin synthesis protein BioH
    • Carboxylesterase BioH

Gene names

    • Name
      bioH
    • ORF names
      BANRA_02043
      , BGM66_002318
      , CTR35_001894
      , E4K51_10190
      , FOI11_018705
      , FOI11_04475
      , G3V95_06145
      , GNW61_08610
      , GRW05_20645
      , HMV95_07990
      , IH772_08660
      , J0541_002162
      , JNP96_25860
      , NCTC9045_00437
      , NCTC9117_00603
      , P6223_000237

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • 1409
    • Escherichia coli
    • EuSCAPE_DE065
    • NCTC9045
    • NCTC9117
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    A0A024KZ56
  • Secondary accessions
    • A0A236RBM4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-242AB hydrolase-1

Sequence similarities

Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    256
  • Mass (Da)
    28,505
  • Last updated
    2014-07-09 v1
  • Checksum
    931226F241BBCBF3
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPAEFCHLLVALKQRV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AASHPR010000013
EMBL· GenBank· DDBJ
EFC3524768.1
EMBL· GenBank· DDBJ
Genomic DNA
AASURL010000030
EMBL· GenBank· DDBJ
EFH0365893.1
EMBL· GenBank· DDBJ
Genomic DNA
AASWOY010000015
EMBL· GenBank· DDBJ
EFH6648805.1
EMBL· GenBank· DDBJ
Genomic DNA
ABLFQU030000002
EMBL· GenBank· DDBJ
EMM0023748.1
EMBL· GenBank· DDBJ
Genomic DNA
DABHXT010000008
EMBL· GenBank· DDBJ
HAJ5958220.1
EMBL· GenBank· DDBJ
Genomic DNA
DADUEU010000011
EMBL· GenBank· DDBJ
HBB1573259.1
EMBL· GenBank· DDBJ
Genomic DNA
JACGTG010000001
EMBL· GenBank· DDBJ
MBA6239287.1
EMBL· GenBank· DDBJ
Genomic DNA
JACZOI010000018
EMBL· GenBank· DDBJ
MBE0977374.1
EMBL· GenBank· DDBJ
Genomic DNA
SQQU01000011
EMBL· GenBank· DDBJ
MQS30537.1
EMBL· GenBank· DDBJ
Genomic DNA
WUIY01000187
EMBL· GenBank· DDBJ
MXI76617.1
EMBL· GenBank· DDBJ
Genomic DNA
JAAGYI010000007
EMBL· GenBank· DDBJ
NEM85089.1
EMBL· GenBank· DDBJ
Genomic DNA
CP063369
EMBL· GenBank· DDBJ
QOY30419.1
EMBL· GenBank· DDBJ
Genomic DNA
CP070393
EMBL· GenBank· DDBJ
QRZ97151.1
EMBL· GenBank· DDBJ
Genomic DNA
UGDD01000002
EMBL· GenBank· DDBJ
STJ52635.1
EMBL· GenBank· DDBJ
Genomic DNA
UGDC01000003
EMBL· GenBank· DDBJ
STJ78083.1
EMBL· GenBank· DDBJ
Genomic DNA
UWVU01000001
EMBL· GenBank· DDBJ
VCW53161.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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