A0A023GU76 · A0A023GU76_9PLEU

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

137750100150200250300350
TypeIDPosition(s)Description
Binding site83Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site97Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site182Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site196Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site201a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      CYTB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Carangaria > Pleuronectiformes > Pleuronectoidei > Achiridae > Trinectes

Accessions

  • Primary accession
    A0A023GU76

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-56Helical
Transmembrane77-98Helical
Transmembrane113-133Helical
Transmembrane140-165Helical
Transmembrane177-200Helical
Transmembrane229-250Helical
Transmembrane288-308Helical
Transmembrane320-341Helical
Transmembrane347-372Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-209Cytochrome b/b6 N-terminal region profile
Domain210-377Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    377
  • Mass (Da)
    41,951
  • Last updated
    2014-07-09 v1
  • Checksum
    320E7735DA5201B2
MTSLRKSHPLLKIANNALIDLPAPASISAWWNFGSLLGLCLITQILTGLFLAMHYTPDISSAFSSVAHICRDVNYGWLIRNVHANGASFFFICLYLHIGRGLYYGSYLYKETWNIGVVLLLLVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVQWIWGGFSVDNATLTRFFAIHFLLPFIIVAVVLVHMIFLHETGSTNPTGLNPNADKIPFHPYFSFKDLLGFAVMLLALTSLALFSPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVIALLSAILILFLVPYLHTAKQRTMTFRPLSQALFWTLVADVVILTWIGAMPVEDPYIIIGQVASVLYFLIFLVLMPLAGLLENKLI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JQ639070
EMBL· GenBank· DDBJ
AFC88466.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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