A0A023FB52 · A0A023FB52_TRIIF

Function

Catalytic activity

  • (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD+ = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H+ + NADH
    This reaction proceeds in the forward direction.
  • (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD+ = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H+ + NADH
    This reaction proceeds in the forward direction.
    EC:1.1.1.232 (UniProtKB | ENZYME | Rhea)
  • 14-hydroxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NAD+ = 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + H+ + NADH
    This reaction proceeds in the forward direction.
  • 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + H+ + NADH = (5S,6R,15S)-trihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD+
    This reaction proceeds in the forward direction.
  • NAD+ + prostaglandin A1 = 15-oxo-prostaglandin A1 + H+ + NADH
    This reaction proceeds in the forward direction.
  • NAD+ + prostaglandin E1 = 15-oxoprostaglandin E1 + H+ + NADH
    This reaction proceeds in the forward direction.
  • NAD+ + prostaglandin E2 = 15-oxoprostaglandin E2 + H+ + NADH
    This reaction proceeds in the forward direction.
    EC:1.1.1.141 (UniProtKB | ENZYME | Rhea)
  • NAD+ + resolvin D1 = 17-oxoresolvin D1 + H+ + NADH
    This reaction proceeds in the forward direction.
  • NAD+ + resolvin D1 = 8-oxoresolvin D1 + H+ + NADH
    This reaction proceeds in the forward direction.
  • NAD+ + resolvin D2 = 16-oxoresolvin D2 + H+ + NADH
    This reaction proceeds in the forward direction.
  • NAD+ + resolvin D2 = 7-oxoresolvin D2 + H+ + NADH
    This reaction proceeds in the forward direction.
  • NAD+ + resolvin E1 = 18-oxo-resolvin E1 + H+ + NADH
    This reaction proceeds in the forward direction.
  • lipoxin A4 + NAD+ = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + H+ + NADH
    This reaction proceeds in the forward direction.

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    15-hydroxyprostaglandin dehydrogenase [NAD(+)]
  • EC number
  • Alternative names
    • Eicosanoid/docosanoid dehydrogenase [NAD(+)]
    • Prostaglandin dehydrogenase 1

Organism names

  • Taxonomic identifier
  • Strain
    • Chile
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Heteroptera > Panheteroptera > Cimicomorpha > Reduviidae > Triatominae > Triatoma

Accessions

  • Primary accession
    A0A023FB52

Subcellular Location

Family & Domains

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    261
  • Mass (Da)
    28,602
  • Last updated
    2014-06-11 v1
  • Checksum
    460651C8C05311B2
MELKGAVALVTGAAQGIGKACVDYLLAEGVKVMITDISKTVGEATEKEMATKHGESNVEFIYCDVTNDECFEDSFKETIKKFDKLDLLINNAGIANELMDDGWKQTIQINFIAVVKGTYLGMKYMGKHEGKPGGTIVNIGSMSSFVPFESTPVYSATKAAVNQFSRSISTKLHYDRTGVRVISVNPAFTDTAILPAITKQIDKSTKTSFLNAWKEHKVQSVDNMGKGMITVLKKAEPGSLWVIQDDVAPKRIELKVIKHDN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GBBI01000005
EMBL· GenBank· DDBJ
JAC18707.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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