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A0A022XY52 · A0A022XY52_TRISD

Function

function

The glycine cleavage system catalyzes the degradation of glycine.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentglycine cleavage complex
Cellular Componentmitochondrion
Molecular Functionglycine binding
Molecular Functionglycine dehydrogenase (decarboxylating) activity
Molecular Functionpyridoxal phosphate binding
Biological Processglycine decarboxylation via glycine cleavage system

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycine cleavage system P protein
  • EC number

Gene names

    • ORF names
      H105_02800

Organism names

  • Taxonomic identifier
  • Strain
    • CBS 452.61
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Arthrodermataceae > Trichophyton

Accessions

  • Primary accession
    A0A022XY52

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue813N6-(pyridoxal phosphate)lysine

Interaction

Subunit

The glycine cleavage system is composed of four proteins: P, T, L and H.

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region66-85Disordered
Domain81-543Glycine cleavage system P-protein N-terminal
Domain564-838Glycine cleavage system P-protein N-terminal
Domain890-1011Glycine dehydrogenase C-terminal

Sequence similarities

Belongs to the GcvP family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,070
  • Mass (Da)
    115,558
  • Last updated
    2014-06-11 v1
  • MD5 Checksum
    39B2934E452FEF2AFFAF57FD48EDB365
MVAALTALRFGGRQLAARQTQAAVLLRATPRQLSPLTACRQCLRSAASRPYRGAAAYRSVHSSAAGGGVTDIQQPLDSFPRRHIGPSQSSAEEMLSVLDPPAKTLDEFVHQVLPADILSAKELGLADPKQTTTKLPRDGLHGGLGESDMIKLFEAYKKDIDTTGRSHIGCGYYGTIVPPVIQRNVLENPIWYTSYTPYQPEISQGRLESLLNFQTLTSDLTGLPVANASVLDEATAAAEAMTMSWAALPANKQKQAGKAFVASHLCHPQTLAVMRSRAQGFGINLIVGDIMADDFKLVKDQGDKLIGVLAQYPDTEGGIYDFQALGNQIHEQGAMFSVATDLLALTVLKAPGEFGADIAFGNSQRFGVPMGFGGPQAAFFACTEKHKRKIPGRIVGVSKDRLGNRALRLALQTREQHIRREKATSNICTAQALLANMSAFYAVYHGPKGLKAIAERTMSLTALLKAKLIALGFNVPTRGNAGGEGVAFDTLVIETSSQAEADSLMEAALASSLYLRRVGSSKVGVSLDETMGLNDVEKLLSVFVKFSPYKGAEAIDLSKDVQPVEIPDSVKRTSSYLTHPVFNSHHSETEMLRYIQHLGSKDLSLAHSMISLGSCTMKLNATTEMLPITWPEFSSVHPFTPAPAVKGYIDMIEDLEKQLANITGMAEVTIQPNSGAQGEFAGLKAIKKYHDSNGDPGKRNICLIPVSAHGTNPASAAMAGMRVVPVKCDTATGNLDVADLRAKCEKHKDELGAIMITYPSTYGVFEPSIKEVCQVVHQYGGQVYMDGANMNAQIGLCSPGEIGADVCHLNLHKTFCIPHGGGGPGVGPIGVAEHLRPFLPSHPLNDHLLAKRPASVDSPPISAAPFGSASILPITFAYINMMGARGLTHATKITLLNANYILSRLKPHFPILYTNANGRCAHEFILDVRQFKASAGIEAIDIAKRLQDYGFHSPTMSFPVANTLMIEPTESESKAELDRFCDALISIRGEIAAIERGEQPKEKNILKLAPHTQRDLLTAEWDRPYTREAAAYPLPWLLEKKFWPTVARVDDAFGDQNLFCTCGPVEDATN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KK208806
EMBL· GenBank· DDBJ
EZF75605.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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