A0A022LUU8 · A0A022LUU8_9ACTN
- Protein3-hydroxyisobutyrate dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids298 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+
Pathway
Amino-acid degradation; L-valine degradation.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 172 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-hydroxyisobutyrate dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | valine catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-hydroxyisobutyrate dehydrogenase
- EC number
- Short namesHIBADH
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Dietziaceae > Dietzia
Accessions
- Primary accessionA0A022LUU8
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 7-163 | 6-phosphogluconate dehydrogenase NADP-binding | |||
Domain | 166-290 | 3-hydroxyisobutyrate dehydrogenase-like NAD-binding | |||
Sequence similarities
Belongs to the HIBADH-related family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length298
- Mass (Da)29,614
- Last updated2014-06-11 v1
- Checksum867D87BC6EB755EF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AOSR01000004 EMBL· GenBank· DDBJ | EYT65414.1 EMBL· GenBank· DDBJ | Genomic DNA |