A0A022L1H3 · A0A022L1H3_9ACTN

  • Protein
    UvrABC system protein A
  • Gene
    uvrA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

110091002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site32-39ATP (UniProtKB | ChEBI)
Binding site651-658ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentexcinuclease repair complex
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Molecular Functionexcinuclease ABC activity
Molecular Functionzinc ion binding
Biological Processnucleotide-excision repair
Biological ProcessSOS response

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    UvrABC system protein A
  • Short names
    UvrA protein
  • Alternative names
    • Excinuclease ABC subunit A

Gene names

    • Name
      uvrA
    • ORF names
      H483_0115690

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • UCD-THP
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Dietziaceae > Dietzia

Accessions

  • Primary accession
    A0A022L1H3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Forms a heterotetramer with UvrB during the search for lesions.

Family & Domains

Features

Showing features for domain, zinc finger, region, compositional bias.

TypeIDPosition(s)Description
Domain618-947ABC transporter
Zinc finger750-776C4-type
Region956-1009Disordered
Compositional bias971-986Polar residues

Sequence similarities

Belongs to the ABC transporter superfamily. UvrA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,009
  • Mass (Da)
    109,586
  • Last updated
    2014-06-11 v1
  • Checksum
    D820709C7D3424D9
MVDRLVVRGAREHNLKGVDIDVPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARMFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVGTITEVYDYLRLLYARAGVPHCPTCGEVVSRQTPQQIVDQILAGEEGVRFQVLAPVVRTRKGEFVDLFAQLAADGYNRVRVDGELHTLAEPPTLKKQEKHDIEVVVDRLAAKPSSRQRLTDSVETALGLADGVIVIDYVDLDETDPARRRRFSEHMACPNGHPIGLDDLEPRAFSFNSPYGACPVCDGLGSHLEVDPDLVIPDPERSLADGAIAPWSGGQSADYFQQLLSGLADDLGFDLRTPWQDLPAKVRKAVLGGASTKVRVRYKNRYGRVRTYDAKFEGVMSFLKRRLEQTESESQKERYQGYMREVPCPACEGTRLKPEILAVTMTGPGGSDRSIADISRMSVADCAEFLDGLELDSRQAMIAGRVLKEIQARMGFLLDVGLDYLSLDRVAGSLSGGEAQRIRLATQIGSGLAGVLYVLDEPSIGLHQRDNRRLIDTLVRLRDLGNTLLVVEHDEDTIRAADWIVDIGPLAGEHGGRVVHSGDYAGLLASTESLTGDYLAGRRSIAVPETRRGLNPEKVLHVRGARENNLKNVDVVFPGGVLCAVTGVSGSGKSTLVNDILATSLANQLNRARQVPGRHSRIDGVESFDKLVQVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYKQGRFSFNVKGGRCEACQGDGTLKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTIAEVLDMPIEEACEFFEPITSIHRYLKTLSQVGLGYVRLGQSAPTLSGGEAQRVKLAAELQKRSSGRTVYILDEPTTGLHFEDITKLLLVIQGLVDKGNTVIVIEHNLDVIKSADWVIDMGPEGGAGGGVVVAEGTPEQVATVPESHTGRFLAQVLPAVQEEPAEGRRPGGKQAGRASAGTTATTKAATTKTVATKAPAKKAAAAKAARKARALR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias971-986Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AOSR01000057
EMBL· GenBank· DDBJ
EYT57316.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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