A0A015TZ89 · A0A015TZ89_BACFG

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

TypeIDPosition(s)Description
Site18Important for substrate specificity
Active site77Proton acceptor
Site78Important for substrate specificity
Site160Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • Name
      maf
    • ORF names
      M125_3647

Organism names

Accessions

  • Primary accession
    A0A015TZ89

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    193
  • Mass (Da)
    21,681
  • Last updated
    2014-06-11 v1
  • Checksum
    E3CA27D3C264572F
MLANLDRYKIVLASNSPRRKELMTGLGVDYVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALGKPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDHYQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JGDB01000232
EMBL· GenBank· DDBJ
EXY89664.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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