A0A014QBG8 · A0A014QBG8_9BURK
- ProteinRibonuclease HII
- GenernhB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids217 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Catalytic activity
Cofactor
Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )
Note: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 26 | a divalent metal cation (UniProtKB | ChEBI) | |||
Binding site | 27 | a divalent metal cation (UniProtKB | ChEBI) | |||
Binding site | 118 | a divalent metal cation (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | ribonuclease H2 complex | |
Molecular Function | manganese ion binding | |
Molecular Function | RNA binding | |
Molecular Function | RNA-DNA hybrid ribonuclease activity | |
Biological Process | DNA replication, removal of RNA primer | |
Biological Process | mismatch repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease HII
- EC number
- Short namesRNase HII
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Comamonas
Accessions
- Primary accessionA0A014QBG8
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length217
- Mass (Da)23,117
- Last updated2014-06-11 v1
- Checksum5E86C732D043B260
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JBOK01000007 EMBL· GenBank· DDBJ | EXU80512.1 EMBL· GenBank· DDBJ | Genomic DNA |