A0A014P1A2 · A0A014P1A2_9BURK
- ProteinAnthranilate phosphoribosyltransferase
- GenetrpD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids344 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
Catalytic activity
- N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate
Cofactor
Note: Binds 2 magnesium ions per monomer.
Pathway
Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 85 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 85 | anthranilate 1 (UniProtKB | ChEBI) | |||
Binding site | 88-89 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 93 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 95-98 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 97 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 113-121 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 125 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 171 | anthranilate 2 (UniProtKB | ChEBI) | |||
Binding site | 230 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 231 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 231 | Mg2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | anthranilate phosphoribosyltransferase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | tryptophan biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAnthranilate phosphoribosyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Comamonas
Accessions
- Primary accessionA0A014P1A2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 7-68 | Glycosyl transferase family 3 N-terminal | |||
Domain | 78-329 | Glycosyl transferase family 3 | |||
Sequence similarities
Belongs to the anthranilate phosphoribosyltransferase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length344
- Mass (Da)36,628
- Last updated2014-06-11 v1
- Checksum9C9E12BCF667E18E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JBOK01000011 EMBL· GenBank· DDBJ | EXU79950.1 EMBL· GenBank· DDBJ | Genomic DNA |