A0A014NIE3 · A0A014NIE3_9GAMM
- ProteinLeucine--tRNA ligase
- GeneleuS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids860 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 622 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | aminoacyl-tRNA editing activity | |
Molecular Function | ATP binding | |
Molecular Function | leucine-tRNA ligase activity | |
Biological Process | leucyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLeucine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Erwiniaceae > Erwinia
Accessions
- Primary accessionA0A014NIE3
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 39-183 | Methionyl/Leucyl tRNA synthetase | |||
Motif | 42-52 | 'HIGH' region | |||
Domain | 221-403 | Leucyl-tRNA synthetase editing | |||
Domain | 417-572 | Aminoacyl-tRNA synthetase class Ia | |||
Domain | 618-653 | Aminoacyl-tRNA synthetase class Ia | |||
Motif | 619-623 | 'KMSKS' region | |||
Domain | 699-821 | Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length860
- Mass (Da)96,737
- Last updated2014-06-11 v1
- MD5 ChecksumA24D7CEB5B2BE774854DA50C6C2D598D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JFHN01000075 EMBL· GenBank· DDBJ | EXU73575.1 EMBL· GenBank· DDBJ | Genomic DNA |