A0A014KZP4 · A0A014KZP4_9ACTN

  • Protein
    Undecaprenyl-diphosphatase
  • Gene
    uppP
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionundecaprenyl-diphosphatase activity
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-diphosphatase
  • EC number
  • Alternative names
    • Bacitracin resistance protein
    • Undecaprenyl pyrophosphate phosphatase

Gene names

    • Name
      uppP
    • ORF names
      Z951_41335

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • PRh5
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A014KZP4

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane46-66Helical
Transmembrane93-115Helical
Transmembrane121-139Helical
Transmembrane192-211Helical
Transmembrane223-245Helical
Transmembrane257-276Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the UppP family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    278
  • Mass (Da)
    29,085
  • Last updated
    2014-06-11 v1
  • Checksum
    F672AC00A27DEDC8
MSAISIGQAAVLGIVEGITEFLPVSSTGHLKITEGLMGIPVDDASVVGFTAVIQVGAIAAVLVYFFKDIVRIVSAWGRGLAHREQRYHHDYKFAWWVICATIPIVIVGLAAKPLIEGPLASLWVVAGSLVAGSGVMWVADQMGRHKRGEDDTGFKDAMLVGCSQILALLFPGFSRSGATMSTALILDLDRVAATRLSFFLGIPALTGAGLYELKDAVGAGVGTAPLVVGTAVSFVVAYASIAWLLKFVAKHSFNAFVVYRVAIGVLLLGLLGTGALTA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABQ01000103
EMBL· GenBank· DDBJ
EXU62476.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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