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A0A013SZ02 · A0A013SZ02_9GAMM

  • Protein
    RNA 3'-terminal phosphate cyclase
  • Gene
    rtcA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site110ATP (UniProtKB | ChEBI)
Binding site291-295ATP (UniProtKB | ChEBI)
Active site316Tele-AMP-histidine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionRNA-3'-phosphate cyclase activity
Biological ProcessRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RNA 3'-terminal phosphate cyclase
  • EC number
  • Short names
    RNA cyclase
    ; RNA-3'-phosphate cyclase

Gene names

    • Name
      rtcA
    • ORF names
      J663_0517

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 826659
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex

Accessions

  • Primary accession
    A0A013SZ02

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain19-333RNA 3'-terminal phosphate cyclase

Sequence similarities

Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    348
  • Mass (Da)
    38,286
  • Last updated
    2014-06-11 v1
  • MD5 Checksum
    0571D37083B4B21C0EBD46DA9008B0DA
MNTVLANMPKAIQIDGSQGEGGGQILRTALTLSMITGQAFELINIRAGRKKPGLMRQHLVCVQASQQISQAYVEGAELHSQRLYFAPQHVQSGKYQFQIGSAGSTTLVLQTLLPVLLLQNEATELTISGGTHNPLAPTADFIEHCFLPALAQIGINVDFKLSKAGFFPIGAGEIQVTVQPWQHRNKLNLLDRGALQSNEAFAAILNLSEEAQIAQRELTTLSKKLNLSSQQQFHLNGISQGNTVYVKVTHQYHTQLFTALGEMRKSAEQIAEHLAKDVNLYLSSQAVVDEYLADQLLLPLALGQGGEFTAQCISEHTRTQAAMIEKFIDCEIEFIELNPHHFHVKVKV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JFYD01000001
EMBL· GenBank· DDBJ
EXS36382.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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