A0A013S522 · A0A013S522_9GAMM
- ProteinHydroxyacylglutathione hydrolase
- GenegloB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids243 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
Catalytic activity
- an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H+
Cofactor
Note: Binds 2 Zn2+ ions per subunit.
Pathway
Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 58 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 60 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 62 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 63 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 116 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 135 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 135 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 173 | Zn2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | hydroxyacylglutathione hydrolase activity | |
Molecular Function | metal ion binding | |
Biological Process | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHydroxyacylglutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex
Accessions
- Primary accessionA0A013S522
Proteomes
Interaction
Subunit
Monomer.
Structure
Sequence
- Sequence statusComplete
- Length243
- Mass (Da)27,674
- Last updated2014-06-11 v1
- MD5 Checksum9C0BD52BF8BD8A5211E9BB4099FF1568
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JFYC01000003 EMBL· GenBank· DDBJ | EXS29479.1 EMBL· GenBank· DDBJ | Genomic DNA |