A0A013RVP3 · A0A013RVP3_9GAMM

  • Protein
    DNA-directed RNA polymerase subunit beta'
  • Gene
    rpoC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site75Zn2+ 1 (UniProtKB | ChEBI)
Binding site77Zn2+ 1 (UniProtKB | ChEBI)
Binding site90Zn2+ 1 (UniProtKB | ChEBI)
Binding site93Zn2+ 1 (UniProtKB | ChEBI)
Binding site465Mg2+ (UniProtKB | ChEBI)
Binding site467Mg2+ (UniProtKB | ChEBI)
Binding site469Mg2+ (UniProtKB | ChEBI)
Binding site819Zn2+ 2 (UniProtKB | ChEBI)
Binding site893Zn2+ 2 (UniProtKB | ChEBI)
Binding site900Zn2+ 2 (UniProtKB | ChEBI)
Binding site903Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionmagnesium ion binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta'
  • EC number
  • Short names
    RNAP subunit beta'
  • Alternative names
    • RNA polymerase subunit beta'
    • Transcriptase subunit beta'

Gene names

    • Name
      rpoC
    • ORF names
      J690_3376

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 742879
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex

Accessions

  • Primary accession
    A0A013RVP3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain240-519RNA polymerase N-terminal

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,397
  • Mass (Da)
    155,109
  • Last updated
    2014-06-11 v1
  • Checksum
    237BEA9E7E3C932F
MKDLLDIMRKKTDSDGHAPIEFDRIRIGLASPEMIKSWSHGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRMKYKGVICEKCGVEVTTAKVRRERMGHIELASPVAHIWFLKSFPSRIGLLLDMTLRDIERVLYFESYVVTDPGMTPFEKYQLLTDEEYFNALEEHGDEFTAKMGAEAVQDLLKDIDLEAEIARLREEIPQTTSETKLKKASKRLKLMEAFKDSNNKPEWMVMNVLPVLPPDLRPLVPLEGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFAKLQASGQATTIKAAKKMVERETPEVWDVLASVIRQHPVMLNRAPTLHRLGLQAFEPILIEGKAIRLHPLVCAAFNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYITRDAVNAKGEGMVFADTHEVNRALATGQVAIHARVKVRVHQTVINENGEREHQTIIVDTTPGRCLLWEIVPQGLSFDMINLEMTKKNISKLINSCYRKLGLKDTVIFADQLMYLGFRQATRSGVSVGMEDMLIPPTKHTIIDKAETEVREIEQQFEQGFVTAGERYNKVVDIWARTNDQVAKAMMDNLSYTLVKNKQGEDEKQKSFNSIYMMSDSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIKANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVITEPDCGTAGGLVMTPFIQGGDVIEPLRDRVLGRVTAEDVRRASDDEVVLPRGTLIDEKIAAQLEEAGVDEVKVRSVIACESTFGVCARCYGRDLARGHLVNPGESVGVMAAQSIGEPGTQLTMRTFHVGGAASRTSAANSVQVRNKGTVRFHNVKTVQHAKGHLVSVSRSGEIGIADDLGRERERYKLPYGASILLKDGEAVEAGGIVATWDPHTHPLVTEVAGKARFSQIADGVTATSKTDDATGMTTVEILPVTARPASGKDLRPAIVLDTTDGGEQFYFLPQNTIVTVRDGETIGVGDVIGRVPQETSRTRDITGGLPRVADLFEARKPKEHAILAEVSGVVSFGKETKGKNRLVITPDDGSEIYEELIPKWRQINVFEGEHVNRGETISDGPQNPHDILRLKGEVALTNYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKVDITDGGDTSFIKGEQVDYIRVVQENQAVLAQNKFPAKFERQLMGITKASLSTDSFISAASFQETTRVLTEAAVTGKEDDLRGLKENVVVGRLIPAGTGLAYHLERRRQEAEAAEHELHNDFSEVDQAFSQALNSEQF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JFYC01000018
EMBL· GenBank· DDBJ
EXS26114.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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