A0A011RN19 · A0A011RN19_9PROT

Function

function

Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site7-14GTP (UniProtKB | ChEBI)
Binding site32-34GTP (UniProtKB | ChEBI)
Active site48GMP-histidine intermediate
Binding site49-52GTP (UniProtKB | ChEBI)
Binding site82GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionadenosylcobinamide kinase (ATP-specific) activity
Molecular Functionadenosylcobinamide kinase (GTP-specific) activity
Molecular FunctionATP binding
Molecular Functioncobinamide phosphate guanylyltransferase activity
Molecular FunctionGTP binding
Biological Processcobalamin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional adenosylcobalamin biosynthesis protein
  • EC number

Gene names

    • Name
      cobP
    • ORF names
      AW12_00502

Organism names

Accessions

  • Primary accession
    A0A011RN19

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the CobU/CobP family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    181
  • Mass (Da)
    19,395
  • Last updated
    2014-06-11 v1
  • Checksum
    AA1857E5AC267D47
MRELIIGGARSGKSLLAERRAGECGLQVVYVATALVLDAEMSRRIEHHKARRSPEWGLVVEPLDLAVALRRHAAPGVCLLVDCLTLWLSNLLFAGEAASQAEAGEVIRCQRLACATQALVELLPELPGRIILVSNEVGCGVVPMAAVSRLFADEQGRLNQRVAAVCERVTLVAAGLPLTLK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JEMZ01000021
EMBL· GenBank· DDBJ
EXI92519.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp