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A0A011NY62 · A0A011NY62_9PROT

Function

function

Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: Binds 1 potassium ion per subunit.

Features

Showing features for binding site.

145850100150200250300350400450
TypeIDPosition(s)Description
Binding site36(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site93(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site132(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site238K+ (UniProtKB | ChEBI)
Binding site238-243GTP (UniProtKB | ChEBI)
Binding site242Mg2+ (UniProtKB | ChEBI)
Binding site257K+ (UniProtKB | ChEBI)
Binding site257-263GTP (UniProtKB | ChEBI)
Binding site259K+ (UniProtKB | ChEBI)
Binding site262K+ (UniProtKB | ChEBI)
Binding site263Mg2+ (UniProtKB | ChEBI)
Binding site282-285GTP (UniProtKB | ChEBI)
Binding site366-368GTP (UniProtKB | ChEBI)
Binding site458(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmetal ion binding
Biological ProcesstRNA methylation
Biological ProcesstRNA wobble uridine modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA modification GTPase MnmE
  • EC number

Gene names

    • Name
      mnmE
    • Synonyms
      trmE
    • ORF names
      AW08_00038

Organism names

Accessions

  • Primary accession
    A0A011NY62

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, coiled coil.

Type
IDPosition(s)Description
Domain228-385TrmE-type G
Coiled coil396-440

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    458
  • Mass (Da)
    49,619
  • Last updated
    2014-06-11 v1
  • MD5 Checksum
    489EEC3549BD59CBB844D9CB0A0030EE
MAERPPTTARPDRAGASDTIAAIATASGRGGIGVIRVSGAGLLDFAQHLSGKRPAPRHATLADFRAADDTVIDCGLLLYFPAPHSFTAEDVLELHGHGGPVVLNMLLSRCLELGARLAEPGEFSRRAYLNGRIDLAQAEAVVDLIDAATTAAARSALRSLQGEFSREVGQLVDQLVELRALVEATLDFPDEEIDFLEAADARGRLDRLQARLARVFERARQGRLLQGGLHVVLAGQPNVGKSSLLNCLAGDDLAIVTAVPGTTRDLVRGTLQLAGVPLHIIDTAGLRETEDQIEKIGIERTWREIERADVVLLLADARHGVGVAEREILARLPAHPTRLTVFNKIDLVPERPQRRQDNNGTIISLSARSGEGVELLRHELLQIAGWQPAEDVFIARERHLQALAAAREHVEMAQAQLLQLELLAEELRLAQRSLAAITGEYSSDDLLGEIFGRFCIGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JFAX01000001
EMBL· GenBank· DDBJ
EXI69545.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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