A0A011MEP6 · A0A011MEP6_9PROT

Function

function

Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site302[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site305[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site348[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site355[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Function4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
Molecular Function4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)
Molecular Functioniron ion binding
Biological Processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Biological Processterpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
  • EC number
  • Alternative names
    • 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase

Gene names

    • Name
      ispG
    • ORF names
      AW07_04417

Organism names

Accessions

  • Primary accession
    A0A011MEP6

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the IspG family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    414
  • Mass (Da)
    44,536
  • Last updated
    2014-06-11 v1
  • MD5 Checksum
    68865D70D0D81D55775C019C1DD4D8C3
MSATSEGTPRRPTRPVRVGQVTIGGAAPVVVQSMTNTDTADIVRTAIQCAELARAGSELVRVTVNTPQAAAAVAPIREQLARMGVDVPLIGDFHYNGHRLLADHPECAEGLAKYRINPGNVGHGRKRDEQFAQMIEIACRYEKPVRIGVNWGSLDQDLLARIMDENARRAVPQDAVAVMREAMVVSALESAARAEALGMPGERIVLSCKVSGVQDLIAIYRELSRRCNYALHLGLTEAGMGSKGIVASTAAMAVLLQEGIGDTIRVSLTPEPGGARTQEVIVAQEMLQTMGLRAFTPMVVACPGCGRTTSTFFQELAQSIQEHVRRRMPLWRIEHDGVENMTLAVMGCVVNGPGESKHANIGISLPGTGEVPAAPVFEDGVKTVTLRGEHIAEEFTAIVDAYVARTYQRKSAVR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JFAW01000050
EMBL· GenBank· DDBJ
EXI68283.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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