A0A010JHF9 · A0A010JHF9_9GAMM
- ProteinAdenosylhomocysteinase
- GeneahcY
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids460 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
Catalytic activity
- S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine
Cofactor
Note: Binds 1 NAD+ per subunit.
Pathway
Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 61 | substrate | |||
Binding site | 137 | substrate | |||
Binding site | 162 | substrate | |||
Binding site | 163-165 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 192 | substrate | |||
Binding site | 196 | substrate | |||
Binding site | 197 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 226-231 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 228-233 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 249 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 298 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 319-321 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 366 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 373 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | adenosylhomocysteinase activity | |
Biological Process | L-homocysteine biosynthetic process | |
Biological Process | one-carbon metabolic process | |
Biological Process | S-adenosylmethionine cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenosylhomocysteinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex
Accessions
- Primary accessionA0A010JHF9
Proteomes
Subcellular Location
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length460
- Mass (Da)50,439
- Last updated2014-06-11 v1
- Checksum19448A5434D048BF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JEYA01000003 EMBL· GenBank· DDBJ | EXE61531.1 EMBL· GenBank· DDBJ | Genomic DNA |