A0A010JHF9 · A0A010JHF9_9GAMM

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site61substrate
Binding site137substrate
Binding site162substrate
Binding site163-165NAD+ (UniProtKB | ChEBI)
Binding site192substrate
Binding site196substrate
Binding site197NAD+ (UniProtKB | ChEBI)
Binding site226-231NAD+ (UniProtKB | ChEBI)
Binding site228-233NAD+ (UniProtKB | ChEBI)
Binding site249NAD+ (UniProtKB | ChEBI)
Binding site298NAD+ (UniProtKB | ChEBI)
Binding site319-321NAD+ (UniProtKB | ChEBI)
Binding site366NAD+ (UniProtKB | ChEBI)
Binding site373NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process
Biological ProcessS-adenosylmethionine cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • ORF names
      J580_1934

Organism names

  • Taxonomic identifier
  • Strain
    • 1542444
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex

Accessions

  • Primary accession
    A0A010JHF9

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain197-372S-adenosyl-L-homocysteine hydrolase NAD binding

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    460
  • Mass (Da)
    50,439
  • Last updated
    2014-06-11 v1
  • Checksum
    19448A5434D048BF
MNAVNASFTDYKVADISLADYGRKEIKLAEAEMPALIGLRKRYAASKPLAGAKILGCIHMTIQTAVLIETLIELGAEVRWTSCNIFSTQDHAAAAIAARGIPVFAWKGETEEEYMWCLEQQVNVNGQPWDANMILDDGGDLTALVHDKYPALLERIHGITEETTTGVQRLIEMWKDGSLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRATDMLLSGRRALVIGYGDVGKGSAQSLRQEGMIVRVTEVDPICAMQACMDGYEVVSPYKNGVQTGKKEDINQDLLGNTDLVVTTTGNYHVCDAAMLDSLKAGAVVCNIGHFDTEIDTAYLRGYKWVEVKPQVHQVYRSEDENNYLILLSEGRLVNLGNATGHPSRVMDGSFANQVLGQIHLFQEKFADLPASEKAEKIRVEVLPKKLDEEVAAAMVAGFGGVLTQLTQEQADYLGVAVEGPFKSDAYKY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JEYA01000003
EMBL· GenBank· DDBJ
EXE61531.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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