A0A009QFR0 · A0A009QFR0_ACIBA
- ProteintRNA-dihydrouridine synthase B
- GenedusB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids341 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
Catalytic activity
- a 5,6-dihydrouridine in tRNA + NAD+ = a uridine in tRNA + NADH + H+
- a 5,6-dihydrouridine in tRNA + NADP+ = a uridine in tRNA + NADPH + H+
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 16-18 | FMN (UniProtKB | ChEBI) | |||
Binding site | 70 | FMN (UniProtKB | ChEBI) | |||
Active site | 100 | Proton donor | |||
Binding site | 139 | FMN (UniProtKB | ChEBI) | |||
Binding site | 169 | FMN (UniProtKB | ChEBI) | |||
Binding site | 200-202 | FMN (UniProtKB | ChEBI) | |||
Binding site | 224-225 | FMN (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | FMN binding | |
Molecular Function | tRNA binding | |
Molecular Function | tRNA dihydrouridine synthase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-dihydrouridine synthase B
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex
Accessions
- Primary accessionA0A009QFR0
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 14-314 | DUS-like FMN-binding | |||
Sequence similarities
Belongs to the Dus family. DusB subfamily.
Belongs to the dus family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length341
- Mass (Da)37,832
- Last updated2014-06-11 v1
- ChecksumA08594FB35F40A34
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JEXD01000003 EMBL· GenBank· DDBJ | EXC09208.1 EMBL· GenBank· DDBJ | Genomic DNA |