W5N7U6 · W5N7U6_LEPOC

Function

function

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentacetylcholine-gated channel complex
Cellular Componentneuron projection
Cellular Componentplasma membrane
Cellular Componentpostsynaptic membrane
Cellular Componentsynapse
Molecular Functionacetylcholine receptor activity
Molecular Functionacetylcholine-gated monoatomic cation-selective channel activity
Biological Processacetylcholine receptor signaling pathway
Biological Processmembrane depolarization

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Acetylcholine receptor subunit epsilon

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Holostei > Semionotiformes > Lepisosteidae > Lepisosteus

Accessions

  • Primary accession
    W5N7U6

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane245-267Helical
Transmembrane279-299Helical
Transmembrane311-334Helical
Transmembrane430-452Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-27
ChainPRO_502226406428-470Acetylcholine receptor subunit epsilon

Keywords

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain29-244Neurotransmitter-gated ion-channel ligand-binding
Domain251-352Neurotransmitter-gated ion-channel transmembrane
Domain385-447Neurotransmitter-gated ion-channel transmembrane

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    470
  • Mass (Da)
    53,392
  • Last updated
    2014-04-16 v1
  • Checksum
    DA9E085B7FFA00DC
MRPRSLTVRLVLAVVLFSLCALHVCENQESRLLKDLMSGYNKRIRPARQPGDKVQVQVKLTLTNLISLNEKEEALTTNVWIEIQWNDYRLAWNSSEHDDISVVRVPYNMVWLPDIVLENNIDGKFDVAYYANVLIHPDGSMYWLPPAIYRSACSVEVTYFPFDWQNCTLVFRSQTYSANEIDIILAVDTGKTIEWVDIDPEAFTENGEWAIRHRPARKVINRRYTPDDLEYQEVHFNLIIQRKPLFYIINIIVPCVLISSLVVLAYFLPAQAGGQKLTVSISVLLAQTVFLFLIAQQIPETSLSVPLIGKYLIFSMFVATLIVTNCVIVLNISLRSPNTHTMSHGIRHLHLSHTCQTPAVHILHLSHSIHTPVAYVGTTASLYKSLAHCAPEIKECVDACNFIAQSTREQNDIGSEMESWVLIGKMIDKVCFWAAILLFSIGTIGIFLMGHYNNVPEYPFPGENKKYAPN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AHAT01030402
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AHAT01030403
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AHAT01030404
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AHAT01030405
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AHAT01030406
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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