T1Q061 · T1Q061_POLSP

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionprotein dimerization activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Hypoxia-inducible factor 1-alpha

Organism names

Accessions

  • Primary accession
    T1Q061

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue4044-hydroxyproline
Modified residue5574-hydroxyproline
Modified residue761(3S)-3-hydroxyasparagine

Keywords

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region1-25Disordered
Domain16-69BHLH
Domain80-148PAS
Domain248-299PAS
Region486-509Disordered
Region623-642Disordered
Compositional bias626-641Polar residues
Region650-683Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    784
  • Mass (Da)
    87,777
  • Last updated
    2013-11-13 v1
  • Checksum
    57F42A72EE8AC1B8
MEVVEVTEKKRVSSDRRKEKSRDAARCRRGKESEVFYELAHELPLPHNVTSHLDKASIMRLILSYLRMRNVLSAAGNTKEESELESQFNNFYLKALDGFVMVLSEDGDMVYLSENVSKCMGLTQFELTGHSLFDFAHPCDHEELREVLTHRTGSTKKGKEQNTERSFFLRMKCTLTNRGRTVNIKSATWKVLHCTGHIRVCDPPKGEQDNCGYKEPPMTSMVLICDPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYQPEDLLGRSVYEYYHALDSDHLTKTHHDLFAKGQATTGQYRMLAKKGGFVWVETQATVIYNTKNSQPQCIVCVNYVLSGVVGEDLVFSLGQTENILKPVESPDADVTKLLMQVDPEESTNSLFEKLKEEPEALTLLAPAAGDTIISLDFSKSDDSEIKKLDAVPLYNDVMLPSSSEKMLMSPLPPTEMVKPLLSSHDPVLNLEVVTKLESNPEPLGISFTIPQTPDLSLPSTTQSSPEPSSPSDYCFNVKTDIYGEFKMDLVEKLFAIDTEVRTPFTTQVADDFDLEMLAPYIPMDDDFQLRTLDQLSPMEPVSASPPDIFHKAQTLVTFTPTAAKYDVMPLMNIVSPLHMMEEVKSAPNSPFSGKNSRTESPIRKSAQPLVKLEEQSNQSHPVTPLISKRPTAFSEELSPKTLAQRKRKLESGLSLSKAVGIGTQLHQHEGTLKRSKASEDSGKEVLTPKTILLLQTDLASRLLACSYENNGLPQLTRYDCEVNAPVQGKQTLLQGEDLIRALDQVN

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias626-641Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JQ031041
EMBL· GenBank· DDBJ
AFU07560.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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