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1 to 25 of 28  Show
  1. 1
    "Cell surface tumor endothelial markers are conserved in mice and humans."
    Carson-Walter E.B., Watkins D.N., Nanda A., Vogelstein B., Kinzler K.W., St Croix B.
    Cancer Res. 61:6649-6655(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 9 and mapped to 11 other entries.

  2. 2
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Strain: C57BL/6J.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50435 other entries.

  3. 3
    "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 88-562 (ISOFORM 2).
    Category: Sequences.
    Strain: C57BL/6J.
    Tissue: Embryo.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 10645 and mapped to 44212 other entries.

  4. 4
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-360, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Tissue: Brain, Kidney and Lung.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 25276 and mapped to 5 other entries.

  5. 5
    Category: Sequences.
    Source: MGI:1916788.

    This publication is cited by 16947 and mapped to 30392 other entries.

  6. 6
    "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R., Suzuki H., Yamanaka I., Kiyosawa H., Yagi K., Tomaru Y., Hasegawa Y., Nogami A., Schonbach C., Gojobori T.
    Hayashizaki Y.
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1916788.

    This publication is cited by 16951 and mapped to 41689 other entries.

  7. 7
    "GenePaint.org: an atlas of gene expression patterns in the mouse embryo."
    Visel A., Thaller C., Eichele G.
    Nucleic Acids Res. 32:D552-D556(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Source: MGI:1916788.

    This publication is mapped to 13879 other entries.

  8. 8
    "ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection."
    Bonuccelli G., Sotgia F., Frank P.G., Williams T.M., de Almeida C.J., Tanowitz H.B., Scherer P.E., Hotchkiss K.A., Terman B.I., Rollman B., Alileche A., Brojatsch J., Lisanti M.P.
    Am J Physiol Cell Physiol 288:C1402-10(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Expression.
    Annotation: This is the first demonstration that the ATR/TEM8 protein is highly expressed in epithelial cells suggesting that the ATR/TEM8 expression pattern is highly relevant for understanding the pathogenesis of anthrax infection.
    Source: GeneRIF:69538.

    This publication is mapped to 4 other entries.

  9. 9
    Category: Sequences.
    Source: MGI:1916788.

    This publication is mapped to 33 other entries.

  10. 10
    "Transcriptional stimulation of anthrax toxin receptors by anthrax edema toxin and Bacillus anthracis Sterne spore."
    Xu Q., Hesek E.D., Zeng M.
    Microb Pathog 43:37-45(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: The mRNA transcripts of both receptors ANTXR1 and ANTXR2 were detected in J774A.1 cells and mouse tissues suggesting that anthrax edema toxin and B. anthracis Sterne spore are involved in the ANTXR mRNA regulation in host cells.
    Source: GeneRIF:69538.

    This publication is mapped to 3 other entries.

  11. 11
    "Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo."
    Liu S., Crown D., Miller-Randolph S., Moayeri M., Wang H., Hu H., Morley T., Leppla S.H.
    Proc Natl Acad Sci U S A 106:12424-12429(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Data show that the lethality of anthrax toxin for mice is mostly mediated by CMG2 and that TEM8 plays only a minor role. [GeneRIF:69538].
    Source: GeneRIF:69538, MGI:1916788.

    This publication is mapped to 8 other entries.

  12. 12
    "Host-derived tumor endothelial marker 8 promotes the growth of melanoma."
    Cullen M., Seaman S., Chaudhary A., Yang M.Y., Hilton M.B., Logsdon D., Haines D.C., Tessarollo L., St Croix B.
    Cancer Res 69:6021-6026(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Host-derived TEM8 promotes the growth of certain tumors. [GeneRIF:69538].
    Source: GeneRIF:69538, MGI:1916788.

    This publication is mapped to 2 other entries.

  13. 13
    "The cell surface structure of tumor endothelial marker 8 (TEM8) is regulated by the actin cytoskeleton."
    Yang M.Y., Chaudhary A., Seaman S., Dunty J., Stevens J., Elzarrad M.K., Frankel A.E., St Croix B.
    Biochim Biophys Acta 1813:39-49(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: MGI:1916788.

    This publication is mapped to 6 other entries.

  14. 14
    Category: Expression.
    Source: MGI:1916788.

    This publication is mapped to 50739 other entries.

  15. 15
    "GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier."
    Cullen M., Elzarrad M.K., Seaman S., Zudaire E., Stevens J., Yang M.Y., Li X., Chaudhary A., Xu L., Hilton M.B., Logsdon D., Hsiao E., Stein E.V., Cuttitta F., Haines D.C., Nagashima K., Tessarollo L., St Croix B.
    Proc. Natl. Acad. Sci. U.S.A. 108:5759-5764(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Source: MGI:1916788.

    This publication is cited by 1 and mapped to 293 other entries.

  16. 16
    Category: Function.
    Source: MGI:1916788.

    This publication is mapped to 6 other entries.

  17. 17
    "TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types."
    Chaudhary A., Hilton M.B., Seaman S., Haines D.C., Stevenson S., Lemotte P.K., Tschantz W.R., Zhang X.M., Saha S., Fleming T., St Croix B.
    Cancer Cell 21:212-226(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:1916788.

    This publication is mapped to 6 other entries.

  18. 18
    "The receptors that mediate the direct lethality of anthrax toxin."
    Liu S., Zhang Y., Hoover B., Leppla S.H.
    Toxins (Basel) 5:1-8(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: These results strongly suggest that TEM8 is the only minor anthrax toxin receptor mediating direct lethality in vivo and that other proteins implicated as receptors do not play this role.
    Source: GeneRIF:69538.
  19. 19
    "Targeted silencing of anthrax toxin receptors protects against anthrax toxins."
    Arevalo M.T., Navarro A., Arico C.D., Li J., Alkhatib O., Chen S., Diaz-Arevalo D., Zeng M.
    J Biol Chem 289:15730-15738(2014) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Anthrax toxin receptors in mouse and human macrophages were silenced using targeted siRNAs or blocked with specific antibody prior to challenge with anthrax lethal toxin.
    Source: GeneRIF:69538.

    This publication is mapped to 12 other entries.

  20. 20
    "Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis."
    Besschetnova T.Y., Ichimura T., Katebi N., St Croix B., Bonventre J.V., Olsen B.R.
    Matrix Biol 42:56-73(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Data demonstrate that TEM8 is an essential regulator of connective tissue homeostasis. it controls synthesis of major matrix components in both endothelial and fibroblastic cells and regulates signaling pathways and matrix degradation. [GeneRIF:69538].
    Source: GeneRIF:69538, MGI:1916788.

    This publication is mapped to 181 other entries.

  21. 21
    "Anthrax Toxin Receptor 1 Is Essential for Arteriogenesis in a Mouse Model of Hindlimb Ischemia."
    Andersen N.J., Boguslawski E.A., Naidu A.S., Szot C., Bromberg-White J.L., Kits K., Kuk C.Y., Holton L.E., St Croix B., Chambers C.M., Duesbery N.S.
    PLoS One 11:e0146586-e0146586(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: An essential physiologic role for Antxr1 in arteriogenesis and peripheral artery disease. [GeneRIF:69538].
    Source: GeneRIF:69538, MGI:1916788.

    This publication is mapped to 2 other entries.

  22. 22
    "Solid tumor therapy by selectively targeting stromal endothelial cells."
    Liu S., Liu J., Ma Q., Cao L., Fattah R.J., Yu Z., Bugge T.H., Finkel T., Leppla S.H.
    Proc Natl Acad Sci U S A 113:E4079-87(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:1916788.

    This publication is mapped to 29 other entries.

  23. 23
    "Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 or TEM8 Receptors for Cellular Uptake and Tumor Targeting."
    Chen K.H., Liu S., Leysath C.E., Miller-Randolph S., Zhang Y., Fattah R., Bugge T.H., Leppla S.H.
    J Biol Chem 291:22021-22029(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 or TEM8 Receptors for Cellular Uptake and Tumor Targeting.
    Source: GeneRIF:69538.

    This publication is mapped to 3 other entries.

  24. 24
    "Cell autonomous ANTXR1-mediated regulation of extracellular matrix components in primary fibroblasts."
    Hu K., Olsen B.R., Besschetnova T.Y.
    Matrix Biol 62:105-114(2017) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: MGI:1916788.

    This publication is mapped to 2 other entries.

  25. 25
    Category: Function, Subcellular Location.
    Source: MGI:1916788.

    This publication is cited by 1 and mapped to 5 other entries.

1 to 25 of 28  Show
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