Q8LCQ4 · LHCA6_ARATH
- ProteinPhotosystem I chlorophyll a/b-binding protein 6, chloroplastic
- GeneLHCA6
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids270 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Seems involved in the function of the photosystem I in low light conditions, when other LHCA proteins are less abundant. Required, together with LHCA5, for the formation of a full-size NAD(P)H dehydrogenase-photosystem I supercomplex (NDH-PSI) that triggers cyclic and chlororespiratory electron transport in chloroplast thylakoids, especially under stress conditions (e.g. increased light intensity).
Cofactor
Note: Binds at least 14 chlorophylls (8 Chl-a and 6 Chl-b) and carotenoids such as lutein and neoxanthin.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 68 | Mg (UniProtKB | ChEBI) of chlorophyll b 1 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 88 | chlorophyll a 1 (UniProtKB | ChEBI) | |||
Binding site | 107 | Mg (UniProtKB | ChEBI) of chlorophyll a 1 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 112 | chlorophyll b 2 (UniProtKB | ChEBI) | |||
Binding site | 165 | Mg (UniProtKB | ChEBI) of chlorophyll b 3 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 168 | chlorophyll b 4 (UniProtKB | ChEBI) | |||
Binding site | 221 | chlorophyll a 5 (UniProtKB | ChEBI) | |||
Binding site | 222 | Mg (UniProtKB | ChEBI) of chlorophyll a 3 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 225 | Mg (UniProtKB | ChEBI) of chlorophyll a 4 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 227 | chlorophyll a 1 (UniProtKB | ChEBI) | |||
Binding site | 239 | Mg (UniProtKB | ChEBI) of chlorophyll a 5 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 254 | Mg (UniProtKB | ChEBI) of chlorophyll a 6 (UniProtKB | ChEBI); axial binding residue | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Cellular Component | chloroplast thylakoid membrane | |
Cellular Component | photosystem I | |
Molecular Function | chlorophyll binding | |
Molecular Function | metal ion binding | |
Biological Process | photosynthesis, light harvesting in photosystem I |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended namePhotosystem I chlorophyll a/b-binding protein 6, chloroplastic
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ8LCQ4
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Plastid, chloroplast thylakoid membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 146-164 | Helical | |||
Transmembrane | 228-244 | Helical | |||
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Slightly lower NDH activity in immature leaves. No chlorophyll fluorescence increase in mature leaves. Smaller version of the NAD(P)H dehydrogenase-photosystem I supercomplex (NDH-PSI) supercomplex (PubMed:19903870).
In the double mutant lhca5 lhca6, drastic reduction of NDH subunits accumulation upon increased light intensity (PubMed:21278308).
In the double mutant lhca5 lhca6, drastic reduction of NDH subunits accumulation upon increased light intensity (PubMed:21278308).
Variants
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We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 16 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transit peptide | 1-33 | Chloroplast | |||
Chain | PRO_0000435450 | 34-270 | Photosystem I chlorophyll a/b-binding protein 6, chloroplastic | ||
Post-translational modification
Photoregulated by reversible phosphorylation of its threonine residues.
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 16-36 | Disordered | |||
Compositional bias | 19-36 | Polar residues | |||
Domain
The N-terminus of the protein extends into the stroma where it is involved with adhesion of granal membranes and post-translational modifications; both are believed to mediate the distribution of excitation energy between photosystems I and II.
Sequence similarities
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length270
- Mass (Da)29,939
- Last updated2002-10-01 v1
- MD5 Checksum5AFF21C30AD39C6B83133420D9E9E672
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 19-36 | Polar residues | |||
Sequence conflict | 21 | in Ref. 4; AAO22627 | |||
Sequence conflict | 29 | in Ref. 1; AAA57542 | |||
Sequence conflict | 67-76 | in Ref. 1; AAA57542 | |||
Sequence conflict | 91 | in Ref. 1; AAA57542 | |||
Sequence conflict | 194 | in Ref. 1; AAA57542 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U03395 EMBL· GenBank· DDBJ | AAA57542.1 EMBL· GenBank· DDBJ | mRNA | ||
AC069143 EMBL· GenBank· DDBJ | AAF82226.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002684 EMBL· GenBank· DDBJ | AEE29811.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT002807 EMBL· GenBank· DDBJ | AAO22627.1 EMBL· GenBank· DDBJ | mRNA | ||
BT020322 EMBL· GenBank· DDBJ | AAV85677.1 EMBL· GenBank· DDBJ | mRNA | ||
BT020554 EMBL· GenBank· DDBJ | AAW70400.1 EMBL· GenBank· DDBJ | mRNA | ||
AY086461 EMBL· GenBank· DDBJ | AAM63464.1 EMBL· GenBank· DDBJ | mRNA |