Q1K6U0 · STUA_NEUCR
- ProteinCell pattern formation-associated protein asm-1
- GeneAsm-1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids643 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Transcription factor that regulates asexual reproduction (PubMed:25550299, PubMed:8913744).
Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).
Required for rapid conidial germination, normal vegetative morphology, and protoperithecium formation (PubMed:8913744).
Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).
Required for rapid conidial germination, normal vegetative morphology, and protoperithecium formation (PubMed:8913744).
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 150-171 | H-T-H motif | ||||
Sequence: GTKLLNVAGMTRGRRDGILKSE |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Biological Process | conidium formation | |
Biological Process | sporulation resulting in formation of a cellular spore |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCell pattern formation-associated protein asm-1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Sordariomycetidae > Sordariales > Sordariaceae > Neurospora
Accessions
- Primary accessionQ1K6U0
Proteomes
Organism-specific databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
Destroys the ability to make protoperithecia (female organs), but does not affect male-specific functions (PubMed:8913744).
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000435980 | 1-643 | Cell pattern formation-associated protein asm-1 | |||
Sequence: MNPNTPADVYYGQMSQGSSMPVTTVPSHSHYASQQPPPLLQPGSTYAHQYGTPQYGYANALSSPASIPPSLPPSMNSMAGQSVLPLPGSGSMNPAVYASGGFDTTGQVAPPGMKPRVTATLWEDEGSLCFQVEARGICVARREDNAMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPFERALDFANKEKITELLYPLFVHNIGALLYHPTNQSRTSQVMAAAEQRRKDSHGQLRGPPGLPSLQQHHHHHSMLPGPPSLPSHPSMGRPALDRAHTFPTPPTSASSVMGPMGNSDGYQWSQQSMSGTQGNSSLSLDTSLGSNARSMPSTPATTPPGSTIQSMQNYPPVSQSYESSRQMYQGQSAQQAQYQSQQHYSSQPQHQERPVYSQSSYIKNDMGPPSGRPTGQSNDASDSKPPTGMIHQGQGQSDPGTHAGSEEDDDANNEAEYTHDSGGYDANRGSYNYNTQAVNSLPHDHGLAPEIGGSPHQAGSGRATPRTAAAPSSYYSAQGYHTPPRGQPSSSLYNVMSNERTGSNGTQGNEMYAGQADMPSSLPNGYSAQPSVMNGSSGGLKRGRDDDDDGGRPTTSAPNLGPGMDMKRRKTMMDGGSLPSPTYTATIAQAAPSAIAAHRRR |
Proteomic databases
Expression
Induction
Constitutively expressed during the mycelial, conidial, and perithecial stages of the life cycle (PubMed:8913744).
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-37 | Disordered | ||||
Sequence: MNPNTPADVYYGQMSQGSSMPVTTVPSHSHYASQQPP | ||||||
Domain | 116-222 | HTH APSES-type | ||||
Sequence: RVTATLWEDEGSLCFQVEARGICVARREDNAMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPFERALDFANKEKITELLYPLFVHNIGALLYHP | ||||||
Region | 229-627 | Disordered | ||||
Sequence: SQVMAAAEQRRKDSHGQLRGPPGLPSLQQHHHHHSMLPGPPSLPSHPSMGRPALDRAHTFPTPPTSASSVMGPMGNSDGYQWSQQSMSGTQGNSSLSLDTSLGSNARSMPSTPATTPPGSTIQSMQNYPPVSQSYESSRQMYQGQSAQQAQYQSQQHYSSQPQHQERPVYSQSSYIKNDMGPPSGRPTGQSNDASDSKPPTGMIHQGQGQSDPGTHAGSEEDDDANNEAEYTHDSGGYDANRGSYNYNTQAVNSLPHDHGLAPEIGGSPHQAGSGRATPRTAAAPSSYYSAQGYHTPPRGQPSSSLYNVMSNERTGSNGTQGNEMYAGQADMPSSLPNGYSAQPSVMNGSSGGLKRGRDDDDDGGRPTTSAPNLGPGMDMKRRKTMMDGGSLPSPTYTA | ||||||
Compositional bias | 289-443 | Polar residues | ||||
Sequence: PTPPTSASSVMGPMGNSDGYQWSQQSMSGTQGNSSLSLDTSLGSNARSMPSTPATTPPGSTIQSMQNYPPVSQSYESSRQMYQGQSAQQAQYQSQQHYSSQPQHQERPVYSQSSYIKNDMGPPSGRPTGQSNDASDSKPPTGMIHQGQGQSDPGT | ||||||
Compositional bias | 467-483 | Polar residues | ||||
Sequence: DANRGSYNYNTQAVNSL | ||||||
Compositional bias | 508-578 | Polar residues | ||||
Sequence: RTAAAPSSYYSAQGYHTPPRGQPSSSLYNVMSNERTGSNGTQGNEMYAGQADMPSSLPNGYSAQPSVMNGS | ||||||
Region | 583-612 | Nuclear localization domain | ||||
Sequence: KRGRDDDDDGGRPTTSAPNLGPGMDMKRRK |
Sequence similarities
Belongs to the EFG1/PHD1/stuA family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length643
- Mass (Da)68,449
- Last updated2011-06-28 v1
- Checksum56B4C1AF11AE44D7
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 289-443 | Polar residues | ||||
Sequence: PTPPTSASSVMGPMGNSDGYQWSQQSMSGTQGNSSLSLDTSLGSNARSMPSTPATTPPGSTIQSMQNYPPVSQSYESSRQMYQGQSAQQAQYQSQQHYSSQPQHQERPVYSQSSYIKNDMGPPSGRPTGQSNDASDSKPPTGMIHQGQGQSDPGT | ||||||
Compositional bias | 467-483 | Polar residues | ||||
Sequence: DANRGSYNYNTQAVNSL | ||||||
Compositional bias | 508-578 | Polar residues | ||||
Sequence: RTAAAPSSYYSAQGYHTPPRGQPSSSLYNVMSNERTGSNGTQGNEMYAGQADMPSSLPNGYSAQPSVMNGS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM002240 EMBL· GenBank· DDBJ | EAA31601.1 EMBL· GenBank· DDBJ | Genomic DNA |