Q0QF04 · Q0QF04_BOVIN

  • Protein
    succinate dehydrogenase
  • Gene
    SDHA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site282Proton acceptor

GO annotations

AspectTerm
Cellular Componentmitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
Molecular Functionelectron transfer activity
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionsuccinate dehydrogenase (quinone) activity
Biological Processmitochondrial electron transport, succinate to ubiquinone
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    succinate dehydrogenase
  • EC number

Gene names

    • Name
      SDHA

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    Q0QF04

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue41Tele-8alpha-FAD histidine

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain5-399FAD-dependent oxidoreductase 2 FAD binding
Domain454-545Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Compositional bias530-548Basic and acidic residues
Region530-557Disordered

Sequence similarities

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    557
  • Mass (Da)
    60,844
  • Last updated
    2006-09-05 v1
  • Checksum
    376B23A2DD16871D
EHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMESGECRGVIALCIEDGSIHRIRARNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPAQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSIKPNAGEESVMNLDKLRFANGSIRTSELRLNMQKSMQSHAAVFRVGSVLQEGCEKISSLYGDLRHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDFKERVDEYDYSKPIQGQQK

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias530-548Basic and acidic residues
Non-terminal residue557

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ402990
EMBL· GenBank· DDBJ
ABD77323.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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