Q0P3X7 · CV039_DANRE

Function

function

Negatively regulates long-term potentiation and modulates adult synaptic plasticity.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentsynapse
Cellular Componentsynaptic cleft
Biological Processnegative regulation of long-term synaptic potentiation
Biological Processregulation of synaptic plasticity

Names & Taxonomy

Protein names

  • Recommended name
    Synaptic plasticity regulator PANTS
  • Alternative names
    • Plasticity-associated neural transcript short

Organism names

Accessions

  • Primary accession
    Q0P3X7
  • Secondary accessions
    • A6H8R2

Proteomes

Organism-specific databases

Subcellular Location

Synapse
Synaptic cleft
Note: Detected in both the presynaptic and postsynaptic regions of the synapse and is secreted from neurons into the synaptic cleft. May be released by neuronal dense core vesicles which mediate the release of cleaved neuropeptides.

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003261331-108Synaptic plasticity regulator PANTS

Post-translational modification

Rapidly degraded by proteolysis following neuronal stimulation, resulting in increased AMPA receptor clustering.

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias58-85Basic and acidic residues
Region58-108Disordered

Sequence similarities

Belongs to the UPF0545 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    108
  • Mass (Da)
    13,037
  • Last updated
    2008-03-18 v2
  • Checksum
    63B0AFBC216AAA26
MAGSQAQWRPPRSCDIYCSELKHCKSLRNRFHEYYTYGRAPDCQQWKQDYQNCKDWEKNHSTQAKDSLQESERKRLADQRKFTPVWELRQKPPSDWHLPLNQGEPQDP

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
B0S5C7B0S5C7_DANREsi:ch211-51h9.6108

Sequence caution

The sequence AAI22394.1 differs from that shown. Reason: Erroneous initiation
The sequence AAI46717.1 differs from that shown. Reason: Erroneous initiation

Features

Showing features for sequence conflict, compositional bias.

TypeIDPosition(s)Description
Sequence conflict28in Ref. 1; AAI46717
Compositional bias58-85Basic and acidic residues
Sequence conflict104in Ref. 1; AAI46717

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC122393
EMBL· GenBank· DDBJ
AAI22394.1
EMBL· GenBank· DDBJ
mRNA Different initiation
BC146716
EMBL· GenBank· DDBJ
AAI46717.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Similar Proteins

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