Q06SM3 · Q06SM3_STECO
- Proteinsuccinate dehydrogenase
- GeneSDHA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids494 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- (R)-malate + a quinone = a quinol + enol-oxaloacetateThis reaction proceeds in the forward direction.
- (S)-malate + a quinone = a quinol + enol-oxaloacetateThis reaction proceeds in the forward direction.
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 276 | Proton acceptor | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | succinate dehydrogenase (quinone) activity | |
Biological Process | electron transport chain | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namesuccinate dehydrogenase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Whippomorpha > Cetacea > Odontoceti > Delphinidae > Stenella
Accessions
- Primary accessionQ06SM3
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 35 | Tele-8alpha-FAD histidine | ||||
Sequence: H |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-393 | FAD-dependent oxidoreductase 2 FAD binding | ||||
Sequence: VVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKHVGGQDQVVPGLYACGEAACASVHGANRLGANSL | ||||||
Domain | 448-494 | Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal | ||||
Sequence: RLNMQKSMQSHAAVFRVGSVLQEGCEKISKLYGDLKHLKTFDRGMVW |
Sequence similarities
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Family and domain databases
Sequence
- Sequence statusFragment
- Length494
- Mass (Da)53,515
- Last updated2006-10-31 v1
- Checksum0DAA68A71A43F694
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: V | ||||||
Non-terminal residue | 494 | |||||
Sequence: W |