UniProtKB - P9WNY7 (DGTL1_MYCTU)
Protein
Deoxyguanosinetriphosphate triphosphohydrolase-like protein
Gene
dgt
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
GO - Molecular functioni
- dGTPase activity Source: GO_Central
GO - Biological processi
- dGTP catabolic process Source: GO_Central
Keywordsi
Molecular function | Hydrolase |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-6570-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Deoxyguanosinetriphosphate triphosphohydrolase-like proteinUniRule annotation |
Gene namesi | Name:dgt Ordered Locus Names:Rv2344c ORF Names:MTCY98.13c |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv2344c |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources | |||
ChainiPRO_0000205310 | 2 – 431 | Deoxyguanosinetriphosphate triphosphohydrolase-like proteinAdd BLAST | 430 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserineCombined sources | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | P9WNY7 |
PRIDEi | P9WNY7 |
PTM databases
iPTMneti | P9WNY7 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 72 – 222 | HDPROSITE-ProRule annotationAdd BLAST | 151 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG4105C4Q Bacteria COG0232 LUCA |
KOi | K01129 |
OMAi | FGVYEDD |
PhylomeDBi | P9WNY7 |
Family and domain databases
CDDi | cd00077 HDc, 1 hit |
HAMAPi | MF_01212 dGTPase_type2, 1 hit |
InterProi | View protein in InterPro IPR006261 dNTPase IPR023023 dNTPase_2 IPR003607 HD/PDEase_dom IPR006674 HD_domain IPR026875 PHydrolase_assoc_dom |
Pfami | View protein in Pfam PF01966 HD, 1 hit PF13286 HD_assoc, 1 hit |
SMARTi | View protein in SMART SM00471 HDc, 1 hit |
TIGRFAMsi | TIGR01353 dGTP_triPase, 1 hit |
PROSITEi | View protein in PROSITE PS51831 HD, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P9WNY7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSASEHDPYD DFDRQRRVAE APKTAGLPGT EGQYRSDFAR DRARVLHSAA
60 70 80 90 100
LRRLADKTQV VGPREGDTPR TRLTHSLEVA QIGRGMAIGL GCDLDLVELA
110 120 130 140 150
GLAHDIGHPP YGHNGERALD EVAASHGGFE GNAQNFRILT SLEPKVVDAQ
160 170 180 190 200
GLSAGLNLTR ASLDAVTKYP WMRGDGLGSQ RRKFGFYDDD RESAVWVRQG
210 220 230 240 250
APPERACLEA QVMDWADDVA YSVHDVEDGV VSERIDLRVL AAEEDAAALA
260 270 280 290 300
RLGEREFSRV SADELMAAAR RLSRLPVVAA VGKYDATLSA SVALKRLTSE
310 320 330 340 350
LVGRFASAAI ATTRAAAGPG PLVRFRADLQ VPDLVRAEVA VLKILALQFI
360 370 380 390 400
MSDPRHLETQ ARQRERIHRV AHRLYSGAPQ TLDPVYAAAF NTAADDAARL
410 420 430
RVVVDQIASY TEGRLERIDA DQLGVSRNAL D
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45132.1 |
PIRi | A70662 |
RefSeqi | NP_216860.1, NC_000962.3 WP_003899281.1, NZ_NVQJ01000012.1 |
Genome annotation databases
EnsemblBacteriai | CCP45132; CCP45132; Rv2344c |
GeneIDi | 885421 |
KEGGi | mtu:Rv2344c mtv:RVBD_2344c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45132.1 |
PIRi | A70662 |
RefSeqi | NP_216860.1, NC_000962.3 WP_003899281.1, NZ_NVQJ01000012.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 83332.Rv2344c |
PTM databases
iPTMneti | P9WNY7 |
Proteomic databases
PaxDbi | P9WNY7 |
PRIDEi | P9WNY7 |
Genome annotation databases
EnsemblBacteriai | CCP45132; CCP45132; Rv2344c |
GeneIDi | 885421 |
KEGGi | mtu:Rv2344c mtv:RVBD_2344c |
Organism-specific databases
TubercuListi | Rv2344c |
Phylogenomic databases
eggNOGi | ENOG4105C4Q Bacteria COG0232 LUCA |
KOi | K01129 |
OMAi | FGVYEDD |
PhylomeDBi | P9WNY7 |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-6570-MONOMER |
Family and domain databases
CDDi | cd00077 HDc, 1 hit |
HAMAPi | MF_01212 dGTPase_type2, 1 hit |
InterProi | View protein in InterPro IPR006261 dNTPase IPR023023 dNTPase_2 IPR003607 HD/PDEase_dom IPR006674 HD_domain IPR026875 PHydrolase_assoc_dom |
Pfami | View protein in Pfam PF01966 HD, 1 hit PF13286 HD_assoc, 1 hit |
SMARTi | View protein in SMART SM00471 HDc, 1 hit |
TIGRFAMsi | TIGR01353 dGTP_triPase, 1 hit |
PROSITEi | View protein in PROSITE PS51831 HD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DGTL1_MYCTU | |
Accessioni | P9WNY7Primary (citable) accession number: P9WNY7 Secondary accession number(s): L0TC18, P0A540, P95240 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | October 16, 2019 | |
This is version 36 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names