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Entry version 25 (16 Oct 2019)
Sequence version 1 (16 Apr 2014)
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Protein

Putative transposase for insertion sequence element IS986/IS6110

Gene

Rv0796

more
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the transposition of the insertion sequence.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processDNA recombination, Transposition

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative transposase for insertion sequence element IS986/IS6110
Alternative name(s):
ORFB
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Rv0796
ORF Names:MTV042.06
AND
Ordered Locus Names:Rv1369c
ORF Names:MTCY02B12.03c
AND
Ordered Locus Names:Rv1756c
ORF Names:MTCY28.22c
AND
Ordered Locus Names:Rv1764
ORF Names:MTCY28.30
AND
Ordered Locus Names:Rv2106
ORF Names:MTCY261.02
AND
Ordered Locus Names:Rv2167c
ORF Names:MTCY270.01
AND
Ordered Locus Names:Rv2279
ORF Names:MTCY339.31c
AND
Ordered Locus Names:Rv2355
ORF Names:MTCY98.24
AND
Ordered Locus Names:Rv2479c
ORF Names:MTV008.35c
AND
Ordered Locus Names:Rv2649
ORF Names:MTCY441.18
AND
Ordered Locus Names:Rv2814c
ORF Names:MTCY16B7.29
AND
Ordered Locus Names:Rv3185
ORF Names:MTV014.29
AND
Ordered Locus Names:Rv3187
ORF Names:MTV014.31
AND
Ordered Locus Names:Rv3326
ORF Names:MTV016.26
AND
Ordered Locus Names:Rv3380c
ORF Names:MTV004.38c
AND
Ordered Locus Names:Rv3475
ORF Names:MTCY13E12.28
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83332 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001584 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

Organism-specific databases

Mycobacterium tuberculosis strain H37Rv genome database

More...
TubercuListi
Rv0796
Rv1369c
Rv1756c
Rv1764
Rv2106
Rv2167c
Rv2279
Rv2355
Rv2479c
Rv2649
Rv2814c
Rv3185
Rv3187
Rv3326
Rv3380c
Rv3475

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000754461 – 278Putative transposase for insertion sequence element IS986/IS6110Add BLAST278

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P9WKH9

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
83332.Rv3475

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini101 – 268Integrase catalyticPROSITE-ProRule annotationAdd BLAST168

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105D4K Bacteria
COG2801 LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
HDVARCT

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025948 HTH-like_dom
IPR038965 InsF-like
IPR001584 Integrase_cat-core
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

The PANTHER Classification System

More...
PANTHERi
PTHR42648 PTHR42648, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13276 HTH_21, 1 hit
PF00665 rve, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994 INTEGRASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P9WKH9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPIAPSTYYD HINREPSRRE LRDGELKEHI SRVHAANYGV YGARKVWLTL
60 70 80 90 100
NREGIEVARC TVERLMTKLG LSGTTRGKAR RTTIADPATA RPADLVQRRF
110 120 130 140 150
GPPAPNRLWV ADLTYVSTWA GFAYVAFVTD AYARRILGWR VASTMATSMV
160 170 180 190 200
LDAIEQAIWT RQQEGVLDLK DVIHHTDRGS QYTSIRFSER LAEAGIQPSV
210 220 230 240 250
GAVGSSYDNA LAETINGLYK TELIKPGKPW RSIEDVELAT ARWVDWFNHR
260 270
RLYQYCGDVP PVELEAAYYA QRQRPAAG
Length:278
Mass (Da):31,369
Last modified:April 16, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE4D33328228D7676
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CCP43544 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP44128 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP44522 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP44530 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP44881 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP44944 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP45061 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP45143 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP45273 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP45447 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP45614 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP45996 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP45998 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP46147 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP46201 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CCP46297 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X52471 Genomic DNA Translation: CAA36710.1
AL123456 Genomic DNA Translation: CCP43544.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44128.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44522.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44530.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44881.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44944.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45061.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45143.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45273.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45447.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45614.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45996.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45998.1 Different initiation.
AL123456 Genomic DNA Translation: CCP46147.1 Different initiation.
AL123456 Genomic DNA Translation: CCP46201.1 Different initiation.
AL123456 Genomic DNA Translation: CCP46297.1 Different initiation.

Protein sequence database of the Protein Information Resource

More...
PIRi
H70567

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CCP43544; CCP43544; Rv0796
CCP44128; CCP44128; Rv1369c
CCP44522; CCP44522; Rv1756c
CCP44530; CCP44530; Rv1764
CCP44881; CCP44881; Rv2106
CCP44944; CCP44944; Rv2167c
CCP45061; CCP45061; Rv2279
CCP45143; CCP45143; Rv2355
CCP45273; CCP45273; Rv2479c
CCP45447; CCP45447; Rv2649
CCP45614; CCP45614; Rv2814c
CCP45996; CCP45996; Rv3185
CCP45998; CCP45998; Rv3187
CCP46147; CCP46147; Rv3326
CCP46201; CCP46201; Rv3380c
CCP46297; CCP46297; Rv3475

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52471 Genomic DNA Translation: CAA36710.1
AL123456 Genomic DNA Translation: CCP43544.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44128.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44522.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44530.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44881.1 Different initiation.
AL123456 Genomic DNA Translation: CCP44944.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45061.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45143.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45273.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45447.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45614.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45996.1 Different initiation.
AL123456 Genomic DNA Translation: CCP45998.1 Different initiation.
AL123456 Genomic DNA Translation: CCP46147.1 Different initiation.
AL123456 Genomic DNA Translation: CCP46201.1 Different initiation.
AL123456 Genomic DNA Translation: CCP46297.1 Different initiation.
PIRiH70567

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi83332.Rv3475

Proteomic databases

PaxDbiP9WKH9

Genome annotation databases

EnsemblBacteriaiCCP43544; CCP43544; Rv0796
CCP44128; CCP44128; Rv1369c
CCP44522; CCP44522; Rv1756c
CCP44530; CCP44530; Rv1764
CCP44881; CCP44881; Rv2106
CCP44944; CCP44944; Rv2167c
CCP45061; CCP45061; Rv2279
CCP45143; CCP45143; Rv2355
CCP45273; CCP45273; Rv2479c
CCP45447; CCP45447; Rv2649
CCP45614; CCP45614; Rv2814c
CCP45996; CCP45996; Rv3185
CCP45998; CCP45998; Rv3187
CCP46147; CCP46147; Rv3326
CCP46201; CCP46201; Rv3380c
CCP46297; CCP46297; Rv3475

Organism-specific databases

TubercuListiRv0796
Rv1369c
Rv1756c
Rv1764
Rv2106
Rv2167c
Rv2279
Rv2355
Rv2479c
Rv2649
Rv2814c
Rv3185
Rv3187
Rv3326
Rv3380c
Rv3475

Phylogenomic databases

eggNOGiENOG4105D4K Bacteria
COG2801 LUCA
OMAiHDVARCT

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR025948 HTH-like_dom
IPR038965 InsF-like
IPR001584 Integrase_cat-core
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PANTHERiPTHR42648 PTHR42648, 1 hit
PfamiView protein in Pfam
PF13276 HTH_21, 1 hit
PF00665 rve, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50994 INTEGRASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTRA9_MYCTU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P9WKH9
Secondary accession number(s): L0TCB7
, O08154, O08156, O08159, O33355, P0C5G8, P19774, P75029, P97137, Q9R378
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2014
Last sequence update: April 16, 2014
Last modified: October 16, 2019
This is version 25 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome, Transposable element

Documents

  1. Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
    Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names
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