P72760 · CCMK1_SYNY3

Function

function

One of the shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered. Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome. The hexamer central pore probably regulates metabolite flux.
Probably the major shell protein of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered. The central pore probably regulates metabolite flux (PubMed:18292340).
Hexamers make sheets that form the facets of the carboxysome (Probable) (PubMed:19844993).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcarboxysome
Molecular Functionstructural constituent of carboxysome shell
Biological Processcarbon fixation
Biological Processphotosynthesis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Carboxysome shell protein CcmK1
  • Alternative names
    • Carbon dioxide-concentrating mechanism protein CcmK1

Gene names

    • Name
      ccmK1
    • Ordered locus names
      sll1029

Organism names

Accessions

  • Primary accession
    P72760

Proteomes

Subcellular Location

Carboxysome
Note: This cyanobacterium makes beta-type carboxysomes (Probable). Forms walls in the polyhedral carboxysome (Probable).

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis92-111Alters hexamer layer packing.

PTM/Processing

Features

Showing features for initiator methionine, chain.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00002015062-111Carboxysome shell protein CcmK1

Proteomic databases

Interaction

Subunit

Homohexamer (PubMed:18292340, PubMed:19177356, PubMed:19844993, PubMed:24419393, PubMed:31603944).
Interacts with full-length CcmM (PubMed:17993516).
Forms mixed heterohexamers of all possible stoichiometries with CcmK2, which might form dodecamers. Only very weak interactions with CcmK3 and CcmK4 were seen (PubMed:31603944).
Interacts with CcmN and CcmO in the carboxysome (By similarity).

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-90BMC

Domain

The tight homohexamer forms a pore with an opening of about 5.0 Angstroms in diameter which is positively charged. Sulfate ions are bound in one crystal form in both the pore and between hexamers which may represent metabolite flux. The C-terminal flexible tail, which is the most variable part of CcmK proteins, seems to be involved in packing of hexamers in layers.

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    111
  • Mass (Da)
    12,102
  • Last updated
    2007-01-23 v3
  • Checksum
    4C3B3E207A600609
MSIAVGMIETLGFPAVVEAADSMVKAARVTLVGYEKIGSGRVTVIVRGDVSEVQASVTAGIENIRRVNGGEVLSNHIIARPHENLEYVLPIRYTEAVEQFREIVNPSIIRR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BA000022
EMBL· GenBank· DDBJ
BAA16775.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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