P42196 · BACS2_NATPH
- ProteinSensory rhodopsin-2
- Genesop2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids239 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Photophobic photoreceptor responsible for the negative phototaxis. Activates the sensory rhodopsin II transducer (HTR-II) in response to blue light.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | monoatomic ion channel activity | |
Molecular Function | photoreceptor activity | |
Biological Process | phototransduction |
Keywords
- Molecular function
- Biological process
- Ligand
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameSensory rhodopsin-2
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloarculaceae > Natronomonas
Accessions
- Primary accessionP42196
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-3 | Extracellular | ||||
Sequence: MVG | ||||||
Transmembrane | 4-25 | Helical; Name=Helix A | ||||
Sequence: LTTLFWLGAIGMLVGTLAFAWA | ||||||
Topological domain | 26-33 | Cytoplasmic | ||||
Sequence: GRDAGSGE | ||||||
Transmembrane | 34-55 | Helical; Name=Helix B | ||||
Sequence: RRYYVTLVGISGIAAVAYVVMA | ||||||
Topological domain | 56-69 | Extracellular | ||||
Sequence: LGVGWVPVAERTVF | ||||||
Transmembrane | 70-91 | Helical; Name=Helix C | ||||
Sequence: APRYIDWILTTPLIVYFLGLLA | ||||||
Topological domain | 92-94 | Cytoplasmic | ||||
Sequence: GLD | ||||||
Transmembrane | 95-117 | Helical; Name=Helix D | ||||
Sequence: SREFGIVITLNTVVMLAGFAGAM | ||||||
Topological domain | 118-121 | Extracellular | ||||
Sequence: VPGI | ||||||
Transmembrane | 122-149 | Helical; Name=Helix E | ||||
Sequence: ERYALFGMGAVAFLGLVYYLVGPMTESA | ||||||
Topological domain | 150-153 | Cytoplasmic | ||||
Sequence: SQRS | ||||||
Transmembrane | 154-181 | Helical; Name=Helix F | ||||
Sequence: SGIKSLYVRLRNLTVILWAIYPFIWLLG | ||||||
Topological domain | 182-189 | Extracellular | ||||
Sequence: PPGVALLT | ||||||
Transmembrane | 190-222 | Helical; Name=Helix G | ||||
Sequence: PTVDVALIVYLDLVTKVGFGFIALDAAATLRAE | ||||||
Topological domain | 223-239 | Cytoplasmic | ||||
Sequence: HGESLAGVDTDAPAVAD |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000196282 | 1-239 | Sensory rhodopsin-2 | |||
Sequence: MVGLTTLFWLGAIGMLVGTLAFAWAGRDAGSGERRYYVTLVGISGIAAVAYVVMALGVGWVPVAERTVFAPRYIDWILTTPLIVYFLGLLAGLDSREFGIVITLNTVVMLAGFAGAMVPGIERYALFGMGAVAFLGLVYYLVGPMTESASQRSSGIKSLYVRLRNLTVILWAIYPFIWLLGPPGVALLTPTVDVALIVYLDLVTKVGFGFIALDAAATLRAEHGESLAGVDTDAPAVAD | ||||||
Modified residue | 205 | N6-(retinylidene)lysine | ||||
Sequence: K |
Interaction
Subunit
Homodimer. Interacts with HTR-II.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | P42196 | htr2 P42259 | 5 | EBI-1034509, EBI-1034515 |
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length239
- Mass (Da)25,355
- Last updated1995-11-01 v1
- ChecksumC0E93EAF341B6B19
Keywords
- Technical term