M3YBQ2 · M3YBQ2_MUSPF

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

1875100200300400500600700800
TypeIDPosition(s)Description
Binding site206Ca2+ 2 (UniProtKB | ChEBI)
Binding site206Ca2+ 1 (UniProtKB | ChEBI)
Binding site289Ca2+ 1 (UniProtKB | ChEBI)
Binding site289Ca2+ 2 (UniProtKB | ChEBI)
Binding site296Ca2+ 1 (UniProtKB | ChEBI)
Binding site347Zn2+ (UniProtKB | ChEBI); catalytic
Active site348
Binding site351Zn2+ (UniProtKB | ChEBI); catalytic
Binding site357Zn2+ (UniProtKB | ChEBI); catalytic
Binding site408Ca2+ 1 (UniProtKB | ChEBI)
Binding site411Ca2+ 1 (UniProtKB | ChEBI)
Binding site411Ca2+ 2 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcollagen-containing extracellular matrix
Cellular Componentextracellular region
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processextracellular matrix organization
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • ADAM metallopeptidase with thrombospondin type 1 motif 8

Gene names

    • Name
      ADAMTS8

Organism names

Accessions

  • Primary accession
    M3YBQ2

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond278↔331
Disulfide bond307↔313
Disulfide bond325↔408
Disulfide bond363↔392
Disulfide bond436↔461
Disulfide bond447↔470
Disulfide bond456↔491
Disulfide bond485↔496
Disulfide bond522↔559
Disulfide bond526↔564
Disulfide bond537↔549

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region95-194Disordered
Compositional bias139-155Basic and acidic residues
Compositional bias156-178Acidic residues
Domain203-413Peptidase M12B

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    875
  • Mass (Da)
    95,499
  • Last updated
    2013-05-01 v1
  • Checksum
    CE66686E19C68DC2
ELVEPTRLPGSAGELAFHLSAFGKGFVLRLEPDASFLAPEFKIERLGGSDPAAGGEQELRDCFFSGTVNGEPESLAAVSLCRGLSGSFLLDGEEFTIQPQGSGGSLRQPHRLQRWGHGARRETPGLAASEAHPLPGGPEWEVKGEDQRQERGDEERESEEVEEEEEMEEEEEGGKEEEAEGASELPPPLGATSRTKRFVSEARFVETLLVADASMAAFYGADLQNHILTLMSVAARIYKHPSIKNAIHLMVVKVLIVEDEKWGPEVSDNGGLTLRNFCSWQRRFNQPSDRHPEHFDTAILLTRQNFCGKEGMCDTLGVADIGTICDPNKSCSVIEDEGLQAAYTLAHELGHVLSMPHDDSKPCARLFGPMGKHHMMAPLFVHLNKTLPWSPCSAMYLTELLDGGHGDCLLDAPTSALPLPSDLPGRRALYELDQQCKQIFGLSFRHCPNTSAQDVCAQLWCHMDGAEPLCHTKNGSLPWADGTPCGPGHLCWDGSCLPEEEVDRPKAVVDGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDAGGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLNPSSYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVNFSTQNSKERATTNVIQPLLNAQWVLGDWSECSSSCGAGWQRRTVECLDPSGQASTTCSEALKPEDAKPCGSQPCPL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias139-155Basic and acidic residues
Compositional bias156-178Acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AEYP01059486
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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