M1KI21 · M1KI21_ENCCN

Function

Catalytic activity

  • Exonucleolytic cleavage of poly(A) to 5'-AMP.
    EC:3.1.13.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentCCR4-NOT complex
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Functionmetal ion binding
Molecular Functionpoly(A)-specific ribonuclease activity
Molecular FunctionRNA binding
Biological Processnuclear-transcribed mRNA poly(A) tail shortening

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    poly(A)-specific ribonuclease
  • EC number
  • Alternative names
    • Carbon catabolite repressor protein 4
    • Cytoplasmic deadenylase
    • Glucose-repressible alcohol dehydrogenase transcriptional effector

Gene names

    • ORF names
      ECU11_0770

Organism names

Accessions

  • Primary accession
    M1KI21

Organism-specific databases

Subcellular Location

Keywords

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain175-468Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the CCR4/nocturin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    493
  • Mass (Da)
    56,489
  • Last updated
    2013-05-01 v1
  • Checksum
    C8C4E4A040A1D52D
MAEECLVSRKKFGGKAMEVRSEMWTGLDLCSQGIKNISKSLFDMRFIRTLNLANNEIEVIPREICNLRHLEVLNLSKNKIRSIPPEIGKIVSLRELNLSDNLISNIPMEMGTLYNLEVFEIANNPLIVPFNTLIRDKKLLQFCREHNTGYPPPNDRLWIECTGKNVFYGDTVSVGTFNILSNIYATRMTYAPSWVINSEFRREGVLQEIVLYNVDILCLQEIELYSFFDFYKEQLEMRCNYDSIIYPRGRVKSVPDKKNVDGCAIFWRRSKFRLIAQFPIDFHQKVIQDTRFNTNQELLDRYGKKDNIAIGALLERPNGQQVLVMNTHIFWDPDYPDIKLLQVLLLVEEIKRVSSRHPNACLLLQGDFNSLRSSSVYKSITTPVIDFADFGDTMQHLSNQQFGDGLGLNDAYSNQDLGFTNFTPGFKGVIDYIFYGGGISLASVLSPVEDEYTENVAGLPNMHFPSDHIFLGAKFAFPNKNISQNAFGRNSRQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KC513604
EMBL· GenBank· DDBJ
AGE94876.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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