J7S130 · J7S130_CAEEL

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcentrosome
Cellular Componentcilium
Cellular Componentcytosol
Cellular Componentlysosomal membrane
Cellular Componentnucleus
Cellular Componentspindle
Molecular FunctionGTPase activator activity
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processpositive regulation of TORC1 signaling
Biological Processpositive regulation of transforming growth factor beta receptor signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Folliculin

Gene names

    • Name
      flcn-1
    • ORF names
      CELE_F22D3.2
      , F22D3.2

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    J7S130

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region147-166Disordered
Domain150-622UDENN FLCN/SMCR8-type

Sequence similarities

Belongs to the folliculin family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    622
  • Mass (Da)
    69,905
  • Last updated
    2012-10-31 v1
  • Checksum
    A193D9407AE93DF8
MQAVIALCHFCENHGPRVVMTCQPMRDVDDKGASCTASTSLGPSTSSSPPGIIVPLIKFDGECVVKEKTNTEDGTSYPHYGNCTKFTIDTEDRCSACSSFRNGPCLLSNDHQTKTSYISSEVALQDRVYERVKNACLRSLSCEVSAASKKNPVQPPPPPLSRSTTPRKIHPYVIHEEPLHDFSGTRIPPSSTVLQEPIEDGAFEQPAAEEADGYVIFGDTDNGFCFAYIFRLADAKARGFYRLFSLIVVSNDLTFLTNNFEYFKTTLGGIKNDLQKLAQDVFSREIDTGEKLSEDDIHKPEFQKLVGKMPSWYRRKIAIDTDRNLTVVTANNDIWVQLHRHMMWTLRSPTLACLDQVMEGKPTQDMMVLLELEESQIVELELRHPNQHLVSMAQLANLKIIATQLNTCSEPGDLDLLIRHIVTGGQVVVESREKEYCRQFLLAISNLLPIGCIKLATYKEQYLPEYSSRFNLIGGPHNMDIPLEVSDVMVFRVSPRDVSIVDIEQMSLVNCVIEVRRRPENDGSNGPLPRIVNRYRDLLLDSDVTDTILETALRTTREGWMLKAKICYQMTKQLSHPQVFEHITGCGVEDQQVVSYWTAGLSNAYKLHVLTSIQQSQTSTAR

Computationally mapped potential isoform sequences

There are 6 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
S6FMZ4S6FMZ4_CAEELflcn-1626
S6F533S6F533_CAEELflcn-1263
S6FCY3S6FCY3_CAEELflcn-1619
Q5DX40Q5DX40_CAEELflcn-1298
K0M7B5K0M7B5_CAEELflcn-1623
S6EZM3S6EZM3_CAEELflcn-1368

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284602
EMBL· GenBank· DDBJ
CCM09388.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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