I6DRB7 · I6DRB7_SHIBO

  • Protein
    Ribonucleoside-diphosphate reductase subunit beta
  • Gene
    nrdF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Note: Binds 2 iron ions per subunit.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site67Fe cation 1 (UniProtKB | ChEBI)
Binding site98Fe cation 2 (UniProtKB | ChEBI)
Binding site101Fe cation 1 (UniProtKB | ChEBI)
Active site105
Binding site158Fe cation 2 (UniProtKB | ChEBI)
Binding site192Fe cation 2 (UniProtKB | ChEBI)
Binding site195Fe cation 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentribonucleoside-diphosphate reductase complex
Molecular Functionmetal ion binding
Molecular Functionribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
Biological Processdeoxyribonucleotide biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonucleoside-diphosphate reductase subunit beta
  • EC number

Gene names

    • Name
      nrdF
    • ORF names
      SB444474_3513

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 4444-74
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Shigella

Accessions

  • Primary accession
    I6DRB7

Proteomes

Interaction

Subunit

Tetramer of two alpha and two beta subunits.

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    304
  • Mass (Da)
    34,772
  • Last updated
    2012-09-05 v1
  • Checksum
    62700FE3625AE5EF
MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLTVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMPYALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKISLGQREELKSFAFDLLLELYDNELQYSDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMAEVNPAILAALSPNADENHDFFSGSRIGN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AKNB01000271
EMBL· GenBank· DDBJ
EIQ34309.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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