C3JY55 · FLUC_PSEFS
- ProteinFluoride-specific ion channel FluC
- GenefluC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids124 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionC3JY55
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 5-25 | Helical | ||||
Sequence: ILAVSAAGIAGTLLRFAAGTW | ||||||
Transmembrane | 38-58 | Helical | ||||
Sequence: TLAVNLVGCLIIGLLYGWFLL | ||||||
Transmembrane | 69-89 | Helical | ||||
Sequence: GLIVGFVGGLTTFSSFSLDTL | ||||||
Transmembrane | 97-117 | Helical | ||||
Sequence: ALIAFGYLGISVFGGLLATWA |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000206260 | 1-124 | Fluoride-specific ion channel FluC | |||
Sequence: MFKTILAVSAAGIAGTLLRFAAGTWVSANWPKHFYAATLAVNLVGCLIIGLLYGWFLLRPEVPIEIRAGLIVGFVGGLTTFSSFSLDTLRLLESGQALIAFGYLGISVFGGLLATWAGLSLTKL |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length124
- Mass (Da)13,108
- Last updated2009-06-16 v1
- Checksum239E1B6D8460C8C0