C3JY55 · FLUC_PSEFS

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site76Na+ (UniProtKB | ChEBI); structural
Binding site79Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      fluC
    • Synonyms
      crcB
    • Ordered locus names
      PFLU_3798

Organism names

Accessions

  • Primary accession
    C3JY55

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane5-25Helical
Transmembrane38-58Helical
Transmembrane69-89Helical
Transmembrane97-117Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10002062601-124Fluoride-specific ion channel FluC

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    124
  • Mass (Da)
    13,108
  • Last updated
    2009-06-16 v1
  • Checksum
    239E1B6D8460C8C0
MFKTILAVSAAGIAGTLLRFAAGTWVSANWPKHFYAATLAVNLVGCLIIGLLYGWFLLRPEVPIEIRAGLIVGFVGGLTTFSSFSLDTLRLLESGQALIAFGYLGISVFGGLLATWAGLSLTKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AM181176
EMBL· GenBank· DDBJ
CAY50101.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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