A5IS24 · SYFA_STAA9
- ProteinPhenylalanine--tRNA ligase alpha subunit
- GenepheS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids352 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H+ + L-phenylalanyl-tRNA(Phe)
Cofactor
Note: Binds 2 magnesium ions per tetramer.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | phenylalanine-tRNA ligase activity | |
Molecular Function | transferase activity | |
Molecular Function | tRNA binding | |
Biological Process | phenylalanyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhenylalanine--tRNA ligase alpha subunit
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus
Accessions
- Primary accessionA5IS24
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000078852 | 1-352 | Phenylalanine--tRNA ligase alpha subunit | |||
Sequence: MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEEKPAFGQKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSFYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM |
Interaction
Subunit
Tetramer of two alpha and two beta subunits.
Structure
Sequence
- Sequence statusComplete
- Length352
- Mass (Da)40,121
- Last updated2007-06-26 v1
- Checksum01FD437729B8FDF7
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000703 EMBL· GenBank· DDBJ | ABQ48997.1 EMBL· GenBank· DDBJ | Genomic DNA |