A0A845MAY6 · A0A845MAY6_9PROT

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site108-111substrate
Active site110Proton acceptor
Binding site130K+ (UniProtKB | ChEBI)
Binding site133ATP (UniProtKB | ChEBI)
Binding site185substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      GQF03_01495

Organism names

  • Taxonomic identifier
  • Strain
    • KCTC 32476
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sneathiellales > Sneathiellaceae > Sneathiella

Accessions

  • Primary accession
    A0A845MAY6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    255
  • Mass (Da)
    27,223
  • Last updated
    2021-09-29 v1
  • Checksum
    FD67A277ACB013E7
MLLAIDVGNTNITCAAYNDRKLVNEWRISTSASRTAEEYGVWLSQAMALDNLKLGDIKDAIVATVVPETLFNIKGFCRRYFGVAPMVIGEAGVDLGMKPLIDNPAEAGADRLVDAVAAHAIYGGPLVVVDFGTGTTLDVVDENGNYIGGVIAPGVNLSLDALHKAAAKLPRIAVARPSRVIGKNTLECMQSGIYWGYIAMIEGLIARIRAEYGENLKVIATGGLAPLFDKGTDIIDHVDADLTLTGLVEIFYKNN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WTVA01000001
EMBL· GenBank· DDBJ
MZR21001.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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