A0A843KH16 · A0A843KH16_9EURY
- ProteinAdenosylcobinamide-GDP ribazoletransferase
- GenecobS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids236 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Catalytic activity
- alpha-ribazole 5'-phosphate + adenosylcob(III)inamide-GDP = adenosylcob(III)alamin 5'-phosphate + GMP + H+
Cofactor
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | adenosylcobinamide-GDP ribazoletransferase activity | |
Molecular Function | cobalamin 5'-phosphate synthase activity | |
Biological Process | cobalamin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenosylcobinamide-GDP ribazoletransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanomicrobiales > Methanomicrobiaceae > Methanoculleus
Accessions
- Primary accessionA0A843KH16
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 35-67 | Helical | ||||
Sequence: AGYVIGGIAAGVVAWIGSPAVGAAVALAVVLVL | ||||||
Transmembrane | 101-120 | Helical | ||||
Sequence: TGAGAVAAGIIVTLVAFAGL | ||||||
Transmembrane | 126-149 | Helical | ||||
Sequence: LWAAILTAEVSAKVAMSYLTTLGV | ||||||
Transmembrane | 161-180 | Helical | ||||
Sequence: GFARPWFVVPATLLALPLFL | ||||||
Transmembrane | 186-205 | Helical | ||||
Sequence: MKIALALVAAAGIAAALLAL |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length236
- Mass (Da)24,265
- Last updated2021-09-29 v1
- ChecksumA3335B1105D67D17