A0A830EPA2 · A0A830EPA2_9EURY

  • Protein
    Transcription initiation factor IIB
  • Gene
    tfb
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

128620406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site8Zn2+ (UniProtKB | ChEBI)
Binding site11Zn2+ (UniProtKB | ChEBI)
Binding site24Zn2+ (UniProtKB | ChEBI)
Binding site27Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionDNA-binding transcription factor activity
Molecular FunctionTBP-class protein binding
Molecular Functionzinc ion binding
Biological Processtranscription preinitiation complex assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription initiation factor IIB
  • Short names
    TFIIB

Gene names

    • Name
      tfb
    • ORF names
      GCM10009067_09720

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • JCM 19018
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloarculaceae > Haloarcula

Accessions

  • Primary accession
    A0A830EPA2

Proteomes

Family & Domains

Features

Showing features for region, domain, repeat.

TypeIDPosition(s)Description
Region40-67Disordered
Domain111-192Cyclin-like
Repeat111-1941
Repeat205-2862
Domain205-286Cyclin-like

Sequence similarities

Belongs to the TFIIB family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    286
  • Mass (Da)
    31,272
  • Last updated
    2021-09-29 v1
  • Checksum
    8EBBA9AFAC9EC541
MSTTVTQCPECNGSVKQQGVESVCGSCGLVVGEDAIDPGPEWRSFNDDDTDRARTGAPLTRSRHDRGLSTKIGRSTRLKGRKRRQFARLRREHNRAQISSKRERNKVYAFTEIRRIVGSMALSDAIRDRACVLFESAQNEALLQGRTLEGFAAAAIYATCRTEGVARTVDELCTVAKATRAELRAAYDALNRELGLPTGPIDPREYVPRFATALDLPTAVRQRAERLVDEAQDRGLVSGRNPAGVAAACLYTAAQEQDVALTQAEAAETADVTPVTLRGTYTELQE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BMPD01000001
EMBL· GenBank· DDBJ
GGK59263.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp