A0A7R7TBX0 · A0A7R7TBX0_THETH

  • Protein
    Leucine--tRNA ligase
  • Gene
    leuS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for binding site.

1878100200300400500600700800
TypeIDPosition(s)Description
Binding site640ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionaminoacyl-tRNA editing activity
Molecular FunctionATP binding
Molecular Functionleucine-tRNA ligase activity
Molecular Functionmetal ion binding
Biological Processleucyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Leucine--tRNA ligase
  • EC number
  • Alternative names
    • Leucyl-tRNA synthetase
      (LeuRS
      )

Gene names

    • Name
      leuS
    • ORF names
      TthHB5018_02170

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HB5018
  • Taxonomic lineage
    Bacteria > Deinococcota > Deinococci > Thermales > Thermaceae > Thermus

Accessions

  • Primary accession
    A0A7R7TBX0

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain37-176Methionyl/Leucyl tRNA synthetase
Motif42-52'HIGH' region
Domain221-406Leucyl-tRNA synthetase editing
Domain419-579Aminoacyl-tRNA synthetase class Ia
Domain580-635Leucyl-tRNA synthetase
Domain718-842Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    878
  • Mass (Da)
    101,089
  • Last updated
    2021-09-29 v1
  • Checksum
    D507E7DB1667B051
MEKYNPHAIEAKWQRFWEEKGFMKAKDLPGGRGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWDAFGLPAENAALKFGVHPKDWTYENIRQAKESLRLMGILYDWDREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKGLVNWCPKCQTVLANEQVVEGRCWRHEDTPVEKRELEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEGKEVRIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGREKTGVFLGAYALNPATGERIPIWTADYVLFGYGTGAIMAVPAHDQRDYEFARKFGLPIKKVIERPGEPLPEPLERAYEEPGIMVNSGPFDGTESEEGKRKVIAWLEEKGLGKGRVTYRLRDWLISRQRYWGTPIPMVHCEACGVVPVPEEELPVLLPDLKDVEDIRPKGKSPLEAHPEFYETTCPKCGGPAKRDTDTMDTFFDSSWYYLRYTDPHNDRLPFDPEKANAWMPVDQYIGGVEHAVLHLLYSRFFTKFLHDLGMVKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTRIRLEIPESALSLENVRKMGAELRPHEDGTLHLWKPAVMSKSKGNGVMVGPFVKEQGADIARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLETSGVFQAEALEGKDRELYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPVTPVYRTAIRYYLQMLFPFAPHLAEELWHWFWPDSLFEAGWPELDEKALEKDVVEVAVQVNGRVRGTIHIPKDAPLEVARAEALKVRNVRAHLEGKEVVKEIYVPGKILNLVVRG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP024270
EMBL· GenBank· DDBJ
BCP65283.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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