A0A7K9V8N1 · A0A7K9V8N1_ANSSE
- ProteinTriosephosphate isomerase
- GeneTpi1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids211 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.
Catalytic activity
- D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | methylglyoxal synthase activity | |
Molecular Function | triose-phosphate isomerase activity | |
Biological Process | gluconeogenesis | |
Biological Process | glyceraldehyde-3-phosphate biosynthetic process | |
Biological Process | glycerol catabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTriosephosphate isomerase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Anseriformes > Anseranatidae > Anseranas
Accessions
- Primary accessionA0A7K9V8N1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusFragment
- Length211
- Mass (Da)22,605
- Last updated2021-04-07 v1
- Checksum9160BCACBC9A8CBC
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: E | ||||||
Non-terminal residue | 211 | |||||
Sequence: H |
Keywords
- Technical term