A0A7C2DBQ1 · A0A7C2DBQ1_UNCAC

  • Protein
    1,4-dihydroxy-2-naphthoyl-CoA synthase
  • Gene
    menB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

hydrogencarbonate (UniProtKB | Rhea| CHEBI:17544 )

Pathway

Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.
Quinol/quinone metabolism; menaquinone biosynthesis.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site31substrate; ligand shared between two neighboring subunits; in other chain
Binding site70-74substrate; ligand shared between two neighboring subunits; in other chain
Binding site82substrate; ligand shared between two neighboring subunits; in other chain
Site82Important for catalysis
Binding site114-118substrate; ligand shared between two neighboring subunits; in other chain
Binding site139-141hydrogencarbonate (UniProtKB | ChEBI)
Binding site140substrate; ligand shared between two neighboring subunits; in other chain
Binding site146substrate; ligand shared between two neighboring subunits; in other chain
Binding site243substrate; ligand shared between two neighboring subunits
Site243Important for catalysis
Binding site258substrate; ligand shared between two neighboring subunits

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function1,4-dihydroxy-2-naphthoyl-CoA synthase activity
Biological Processmenaquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    1,4-dihydroxy-2-naphthoyl-CoA synthase
  • EC number
  • Short names
    DHNA-CoA synthase

Gene names

    • Name
      menB
    • ORF names
      ENP16_11335
      , ENP36_07705

Organism names

Accessions

  • Primary accession
    A0A7C2DBQ1

Subcellular Location

Family & Domains

Sequence similarities

Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    270
  • Mass (Da)
    29,814
  • Last updated
    2020-12-02 v1
  • Checksum
    CEDE95ACECEA1D17
MDWRPSGEWEDIAYETAEGIAKITIDRPEVRNAFRPKTLFELSRAFDLARDDPGIGAIILTGRGPLAFCSGGDQRVRGDDGYRDERGIGRLNVLDLQVQIRRLPKPVVAMVAGYAIGGGHVLHLVCDLTIAAENAVFGQTGPRVGSFDAGFGAGLLARTIGLKRAKEVWFLCRRYDARQALAWGLVNAVVPLERLEEETVAWCREMLRLSPLALRLLKAGFNADIDGLTGVQQLAGDATLLYYMTDEAQEGRDAYLGKRPPDFSRFPRRP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DSJA01000092
EMBL· GenBank· DDBJ
HEJ76894.1
EMBL· GenBank· DDBJ
Genomic DNA
DSIG01000158
EMBL· GenBank· DDBJ
HEP09513.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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