A0A6P5Q309 · A0A6P5Q309_MUSCR

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 2 calcium ions per subunit.

Features

Showing features for binding site, active site.

135550100150200250300350
TypeIDPosition(s)Description
Binding site53Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site54Ca2+ 2 (UniProtKB | ChEBI)
Active site115Proton acceptor
Binding site117Ca2+ 2 (UniProtKB | ChEBI)
Binding site168Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site169Ca2+ 2 (UniProtKB | ChEBI)
Binding site224Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site269Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site270Ca2+ 1 (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functionacyl-L-homoserine-lactone lactonohydrolase activity
Molecular Functionarylesterase activity
Molecular Functionmetal ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Paraoxonase
  • EC number

Gene names

    • Name
      Pon1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    A0A6P5Q309

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
Signal1-15
ChainPRO_502813935916-355Paraoxonase
Disulfide bond42↔353In form B
Glycosylation253N-linked (GlcNAc...) asparagine
Glycosylation270N-linked (GlcNAc...) asparagine
Glycosylation324N-linked (GlcNAc...) asparagine

Post-translational modification

Glycosylated.

Keywords

Family & Domains

Sequence similarities

Belongs to the paraoxonase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    355
  • Mass (Da)
    39,497
  • Last updated
    2020-12-02 v1
  • Checksum
    DC061D858A0F4333
MAKLLALTLVGLVLALYKNHRSSYQTRLNAFREVTPVELPNCNLVKGIETGAEDLEILPNGLTFFSTGLKYPGIKSFDPSKPGKILLMDLNKKEPAVSELEIIGNTLDISSFNPHGISTFTDEDNTVYLLVVNHPDSSSTVEVFKFQEEESSLLHLKTITHELLPSINDIAAIGPESFYATNDHYFADPYLRSWEMYLGLSWSNVVYYSPDKVQVVAEGFDFANGIGISLDGKYVYIAELLAHKIHVYEKHANWTLTPLKVLDFDTLVDNISVDPVTGDLWVGCHPNGMRIFFYDAENPPGSEVLRIQNILSEDPKVTVVYAENGTILQGTTVASVYKGKLLIGTVFHKALYCDL

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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