A0A6J3RVU9 · A0A6J3RVU9_TURTR

Function

function

Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows broad substrate specificity and can also accept deoxyuridine and other analogous compounds.

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.

Features

Showing features for binding site.

124620406080100120140160180200220240
TypeIDPosition(s)Description
Binding site30phosphate (UniProtKB | ChEBI)
Binding site74-77phosphate (UniProtKB | ChEBI)
Binding site153substrate
Binding site155substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functiondeoxyuridine phosphorylase activity
Molecular Functionuridine phosphorylase activity
Biological Processnucleotide catabolic process
Biological ProcessUMP salvage
Biological Processuridine catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridine phosphorylase
  • EC number

Gene names

    • Name
      UPP1

Organism names

Accessions

  • Primary accession
    A0A6J3RVU9

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain27-240Nucleoside phosphorylase

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    246
  • Mass (Da)
    27,133
  • Last updated
    2020-10-07 v1
  • Checksum
    18328A76C682F4AF
MKAFIKYMAVELGLDHPGAEYPDICEGTDRYAMFKVGPVLSVSHGMGIPSIAIMLHELIKLLYHARCSDITLIRIGTSGGIGLEPGSVVITRQAVDGCFKQEFEQIVLGKRVVRNTHLDDWLVQELVRCSADLGEFPTVVGNTMCTLDFYEGQGRLDGALCSYAEKDKQEYLRAAYEAGIRNIEMESSVFAAMCNACGLRAAVVCVTLLNRLEGDQISSPHEVLVEYQQRPQRLVGHFIKKCLAAS

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A6J3RVR7A0A6J3RVR7_TURTRUPP1309
A0A6J3RWB7A0A6J3RWB7_TURTRUPP1291

Keywords

Sequence databases

Similar Proteins

Disclaimer

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