A0A6B0R3X5 · A0A6B0R3X5_9CETA

  • Protein
    Coiled-coil domain-containing protein 39
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxoneme
Cellular Componentextracellular region
Biological Processcilium-dependent cell motility
Biological Processepithelial cilium movement involved in determination of left/right asymmetry
Biological Processinner dynein arm assembly

Names & Taxonomy

Protein names

  • Recommended name
    Coiled-coil domain-containing protein 39

Gene names

    • ORF names
      E5288_WYG021541

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • WY2019
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0A6B0R3X5

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for coiled coil, region.

TypeIDPosition(s)Description
Coiled coil152-183
Coiled coil208-305
Coiled coil369-408
Coiled coil581-608
Coiled coil650-684
Coiled coil713-740
Region784-858Disordered

Sequence similarities

Belongs to the CCDC39 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    858
  • Mass (Da)
    100,006
  • Last updated
    2020-06-17 v1
  • Checksum
    8572F71E11373EA3
MSSEFLAELRWEDGFAIPVANEENKTLEEQNSIFKTTQKLDGLKCQMNWDQQALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLERLTVECNQRRKVLDNEFAETLSVQLELDKAAQDFRKIHNERQKLILQWESTIEQMQKRDKDIDNCAVALARIKQEIREKENLVKEKIKFLENEIGNNTEYEKKISVADRKVLKCRTEYQRHEANRIQLKDELDSLKATVNRSSSDLEALRKNISKVKMDINEETARLGKIKNHNQIVRKKLKEITEKTMSVEEKATNLEDMLREEERGVKEVEVQLNIVKDVLFKKVQELQTETMKEKALVSEIEGTRSSLKHLNHQLHKLDFETLQQQEIMYAQDFYIQQVERRMSRLKGDINSEEKQALEAKTVELQKTLEEKKSALCLLETQIKKLHNDLYFTKKSNSKYRDEKQSLMTKINELTLFNDRSEKELTKAKALKQDLMIEDNLLKLEVKRTRELLHSKAEEVLSLEKRKQQLHTAMEERTEEIKVHKTMLASQIRYVDQERQNISAEFHERLSKIDKLKNRYEILTTFFCPRPHPPAMINTFNQSILFCFKQAAQEKEELQREGDSLDAKINKAEKEIYALGNTLQVLNSCNNNYKQSFQKVTPSSAEYEVKIQLEEQKRAVDEKYRYKQRQIRELQEDIQSMENTLTVIEHLTNNVKEKVTEKQAYVLQLNRETEEQKPKLERVTKQCAKLTKEVRLLKDTKDETLEEQDIKLREVKQLHKIIDEMIVDITQENAEIGVILQTYFQQSGLELPTTSTKGSRHSSRSPSQTSLLSARSSKSTSTSASQTSIKVLELNFPASPLTGSTSRPTSASSASSTGKSRKTNK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VBQZ03000023
EMBL· GenBank· DDBJ
MXQ84879.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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