A0A671NMC6 · A0A671NMC6_9TELE

Function

function

Receptor for ATP that acts as a ligand-gated ion channel.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site67-69ATP (UniProtKB | ChEBI)
Binding site187ATP (UniProtKB | ChEBI)
Binding site294-296ATP (UniProtKB | ChEBI)
Binding site314ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentlysosomal membrane
Cellular Componentplasma membrane
Cellular Componentpostsynapse
Molecular FunctionATP binding
Molecular Functionextracellularly ATP-gated monoatomic cation channel activity
Molecular Functionpurinergic nucleotide receptor activity
Biological Processresponse to ATP

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    P2X purinoceptor

Gene names

    • Name
      p2rx4

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Cyprinidae > Cyprininae > Sinocyclocheilus

Accessions

  • Primary accession
    A0A671NMC6

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Lysosome membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane340-362Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond, glycosylation.

TypeIDPosition(s)Description
Disulfide bond117↔166
Disulfide bond127↔150
Disulfide bond133↔160
Glycosylation185N-linked (GlcNAc...) asparagine
Disulfide bond218↔228
Disulfide bond262↔271

Keywords

PTM databases

Interaction

Subunit

Functional P2XRs are organized as homomeric and heteromeric trimers.

Family & Domains

Sequence similarities

Belongs to the P2X receptor family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    384
  • Mass (Da)
    43,645
  • Last updated
    2020-06-17 v1
  • Checksum
    9F129CC87B441BC2
MGRSWKELGECFFDYYTSKILVIRSRKVGTLNRFTQALVIAYVVGYVCVLKKGYQDTDTVLSSVTTKVKGIALTNTTELGERIWDVADYIIPPQVEDGSFFVLTNMIITPNQTQSKCAENPTPASICTSHRDCKRGFNDARGDGVQTGRCVNYNDTVKTCEVLSWCPLEKIVEPPNPPLLADAENFTVLIKNNIRYPKFNFNKRNILPNINSSYLTQCVFSRKTDPDCPIFRLKDIVEEAEEDFQTMAVHGGVMGVQIRWDCDLDMPQSWCVPRYTFRRLDNKDPENNVAPGYNFRFAKYYKDSDGTETRTLIKGYGIRFDVLVFGQAGKFNIIPTLLNIGAGLALLGLVNVICDWIVLTIMTRKHHYKEQKYTYVDDFGLVSI

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A671NIZ8A0A671NIZ8_9TELEp2rx4399
A0A671NR68A0A671NR68_9TELEp2rx4391
A0A671NM71A0A671NM71_9TELEp2rx4370
A0A671NMI7A0A671NMI7_9TELEp2rx4378
A0A671NKA7A0A671NKA7_9TELEp2rx4367
A0A671NKM4A0A671NKM4_9TELEp2rx4367
A0A671NHZ3A0A671NHZ3_9TELEp2rx4388
A0A671NIL4A0A671NIL4_9TELEp2rx4368

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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