A0A521DYU1 · A0A521DYU1_9BACT

  • Protein
    Transcription termination factor Rho
  • Gene
    rho
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site.

151850100150200250300350400450500
TypeIDPosition(s)Description
Binding site268-273ATP (UniProtKB | ChEBI)
Binding site280-285ATP (UniProtKB | ChEBI)
Binding site311ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent activity, acting on RNA
Molecular Functionhelicase activity
Molecular FunctionRNA binding
Biological ProcessDNA-templated transcription termination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Transcription termination factor Rho
  • EC number
  • Alternative names
    • ATP-dependent helicase Rho

Gene names

    • Name
      rho
    • ORF names
      SAMN06265219_109170

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 21985
  • Taxonomic lineage
    Bacteria > Balneolota > Balneolia > Balneolales > Balneolaceae > Gracilimonas

Accessions

  • Primary accession
    A0A521DYU1

Proteomes

Interaction

Subunit

Homohexamer. The homohexamer assembles into an open ring structure.

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region50-134Disordered
Compositional bias68-89Basic and acidic residues
Domain150-225Rho RNA-BD

Sequence similarities

Belongs to the Rho family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    518
  • Mass (Da)
    58,744
  • Last updated
    2019-10-16 v1
  • Checksum
    EC6F7523E25A999E
MSDNETAGLTAGELESLEGKKLHELQKLAKSIGISRVTGIRKAQLIEEIRKKASEQDLFDQAEDKDKDDEADDRQKNDSAQKDEELKNYGGQSHIVSYNKKEEKDDKKKSNKKRPHSNKRKGHEHNKLPESDAPTLQERIEELEPDLGPYLFNEGTLEILPDGYGFLRSVNYNYKASPDDIYVSPSQIKRFRLKQGDCVIGVIRPPKVGERYFALLRIEGVNGRIPHDMDNRQDFEDLLPIHPDQRYRLEYDAKEHTTRLIDLFAPVGKGQRGLIVAQPKTGKTTILRNIANAVSANSPDTKILIVLIDERPEEVTEMERTVEGAEVVASTFDEKPENHIGLAEIVFEKAKRLVESGHDVLLLMDSITRLARAYNVVASNKGRTMTGGVDSEALKAPRQLFSSARNIENGGSLTILATALIDTGSRMDDVIFEEFKGTGNMEIYLDRRISERRVYPAIDIFRSGTRREELLVDEAEREKVVLLRRYLTNMSPYEAMDFLLDKIKGTKNNEDFLISMNK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias68-89Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FXTP01000009
EMBL· GenBank· DDBJ
SMO76050.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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